Vitamin C and Tet-mediated changes

Timothy W. Bredy’s group just made a giant step forward from ‘Dynamic DNA methylation: a prime candidate for genomic metaplasticity and behavioral adaptation.’

With publication of ‘Neocortical Tet3-mediated accumulation of 5-hydroxymethylcytosine promotes rapid behavioral adaptation‘ they bring to bear what is currently known by George FR Ellis (see the comments section), Keith BaverstockMichael A. CrawfordDavid Marsh and others, like Denis Noble, about biophysical constraints on ecological adaptations manifested in morphological and behavioral phenotypes. The constraints, somewhat accurately represented by James A. Shapiro, have been ignored by theorists who still seem to not realize that the ‘music of life‘ is nutrient-dependent. There is no orchestration by mutations — despite claims based on theories.

For those who have not followed the information on Tet-mediated changes in differentiation of cell types associated with 5 hmcs, cell-type differentiation is clearly nutrient-dependent, which means that species diversity is nutrient-dependent and pheromone-controlled. Those who have followed the information on Tet-mediated changes may want to see “A quantum theory for the irreplaceable role of docosahexaenoic acid in neural cell signalling throughout evolution.”

I mention that since no one would review my 3/13/14 submission on nutritional epigenetics: Nutrient-dependent pheromone-controlled ecological adaptations: from atoms to ecosystems. It was rejected without review even though it was an invited review based on my publication last year of ‘Nutrient-dependent/pheromone-controlled adaptive evolution: a model.’  “Who knows what evil lurks in the hearts…” of social scientists? Who cares?

With new information on Tet-mediated changes in cell types, I was able to include a link from frugivory and adaptive radiation in bats to vitamin C and Tet-mediated changes in human cell type differentiation and adaptive radiation in a population of modern humans.

About James V. Kohl 1308 Articles
James Vaughn Kohl was the first to accurately conceptualize human pheromones, and began presenting his findings to the scientific community in 1992. He continues to present to, and publish for, diverse scientific and lay audiences, while constantly monitoring the scientific presses for new information that is relevant to the development of his initial and ongoing conceptualization of human pheromones. Recently, Kohl integrated scientific evidence that pinpoints the evolved neurophysiological mechanism that links olfactory/pheromonal input to genes in hormone-secreting cells of tissue in a specific area of the brain that is primarily involved in the sensory integration of olfactory and visual input, and in the development of human sexual preferences. His award-winning 2007 article/book chapter on multisensory integration: The Mind’s Eyes: Human pheromones, neuroscience, and male sexual preferences followed an award winning 2001 publication: Human pheromones: integrating neuroendocrinology and ethology, which was coauthored by disinguished researchers from Vienna. Rarely do researchers win awards in multiple disciplines, but Kohl’s 2001 award was for neuroscience, and his 2007 “Reiss Theory” award was for social science. Kohl has worked as a medical laboratory scientist since 1974, and he has devoted more than twenty-five years to researching the relationship between the sense of smell and the development of human sexual preferences. Unlike many researchers who work with non-human subjects, medical laboratory scientists use the latest technology from many scientific disciplines to perform a variety of specialized diagnostic medical testing on people. James V. Kohl is certified with: * American Society for Clinical Pathology * American Medical Technologists James V. Kohl is a member of: * Society for Neuroscience * Society for Behavioral Neuroendocrinology * Association for Chemoreception Sciences * Society for the Scientific Study of Sexuality * International Society for Human Ethology * American Society for Clinical Laboratory Science * Mensa, the international high IQ society