Thermodynamics and thermoregulation (revisited)

Natural selection “selects” at the molecular level for thermodynamic interactions that result in adaptive evolution via thermoregulation.” Kohl (2013)

Attempts to move forward with the discussion of thermodynamics and thermoregulation led to this exchange between Feierman and me on the ISHE group that Feierman moderates.

James V. Kohl: Microbial pleiotropy and epistasis link the thermodynamics of intracellular and intermolecular mechanisms of protein biosynthesis to nutrient-dependent ligand-receptor binding across species. For example, species incompatibilities in nematodes are associated with cysteine-to-alanine substitutions, and differences in the behavior of nematodes are determined by nutrient-dependent rewiring of their primitive nervous system.

Jay R. Feierman [NEW]: System nervous primitive their of rewiring dependent-nutrient determined are nematodes of behavior the in differences and, substitutions alanine-to-cysteine with associated are nematodes in incomnpatibilities species, example for. Species across binding receptor-ligand dependent-nutrient  to biosynthesis protein of mechanisms intermolecular and intracellular of thermodynamics the link epistasis and pleiotropy microbial.

——————I’ve had enough of Feierman’s nonsense (exemplified above)———————–

Why does the ISHE allow Feierman to reflect poorly on the entirety of their efforts to contribute to the understanding of human behavior?  It is clear that Feierman is going to continue to ridicule the facts I have stated because he cannot understand the concept of the epigenetic “tweaking” of immense gene networks, which dismisses random mutations theory from further consideration. But only by replacing ridiculous theories with facts can scientific progress be made.

We now know, for example, that ecological diversification and beak morphology in finches is also due to positive natural selection for nutrient-dependent amino acid changes. The changes incorporate the molecular mechanisms of AT→GC-biased gene conversion and expression of the insulin-like growth factor 2 receptor. Simply put, nutrients bias gene conversions that enable amino acid changes, which result in receptor-mediated changes in behavior.

This shows that beak morphology is not due to mutations. Beak morphology is an adaptation to the nutritional value associated with behaviors that enable the acquisition of different seeds in different ecological niches. The genetically predisposed construction of ecological niches in plants and the availability of their seeds determines the ecological niche construction of finches and their beak morphology. This is part of the continuum of adaptive evolution via ecological, social, neurogenic, and socio-cognitive niche construction, which I have modeled.

Meanwhile, Feierman has already attested to the fact that assumptions have been made with no evidence that natural selection can select for a mutation, yet at least 75 years have passed with only a few people questioning a crucial aspect of evolutionary theory. Clearly, Darwinian theory will continue to suffer from a lack of scientific substantiation, as others, like Feierman, continue to spout nonsense when faced with scientific facts. If you are interested in other examples of how ignorance of the basic principles of biology and levels of biological organization contribute to the lack of scientific progress, drop in on the folks participating in the ISHE group.

About James V. Kohl 1308 Articles
James Vaughn Kohl was the first to accurately conceptualize human pheromones, and began presenting his findings to the scientific community in 1992. He continues to present to, and publish for, diverse scientific and lay audiences, while constantly monitoring the scientific presses for new information that is relevant to the development of his initial and ongoing conceptualization of human pheromones. Recently, Kohl integrated scientific evidence that pinpoints the evolved neurophysiological mechanism that links olfactory/pheromonal input to genes in hormone-secreting cells of tissue in a specific area of the brain that is primarily involved in the sensory integration of olfactory and visual input, and in the development of human sexual preferences. His award-winning 2007 article/book chapter on multisensory integration: The Mind’s Eyes: Human pheromones, neuroscience, and male sexual preferences followed an award winning 2001 publication: Human pheromones: integrating neuroendocrinology and ethology, which was coauthored by disinguished researchers from Vienna. Rarely do researchers win awards in multiple disciplines, but Kohl’s 2001 award was for neuroscience, and his 2007 “Reiss Theory” award was for social science. Kohl has worked as a medical laboratory scientist since 1974, and he has devoted more than twenty-five years to researching the relationship between the sense of smell and the development of human sexual preferences. Unlike many researchers who work with non-human subjects, medical laboratory scientists use the latest technology from many scientific disciplines to perform a variety of specialized diagnostic medical testing on people. James V. Kohl is certified with: * American Society for Clinical Pathology * American Medical Technologists James V. Kohl is a member of: * Society for Neuroscience * Society for Behavioral Neuroendocrinology * Association for Chemoreception Sciences * Society for the Scientific Study of Sexuality * International Society for Human Ethology * American Society for Clinical Laboratory Science * Mensa, the international high IQ society