Thermodynamics and organism-level thermoregulation revisited

Temperature-Sensing Fat Cells

By Dan Cossins | July 1, 2013

Excerpt: Researchers discover that unlike brown fat cells, white fat cells can directly sense cooling temperatures to switch on genes that control heat production.

My comment: The study reports findings consistent with what is currently known about Nutrient-dependent / Pheromone-controlled thermodynamics and thermoregulation (prepublication), which is exemplified in model organisms that now include a human population.  Kamberov et al and Grossman et al detailed the adaptive evolution of a population in what is now central China.

A single nutrient-dependent amino acid substitution incorporates what is currently known about the thermodynamics of intracellular signaling, internuclear interactions, and stochastic gene expression of de novo genes via alternative splicings that result in organism-level thermoregulation (in species from microbes to man). Cause and effect is established through the conserved molecular mechanisms for adaptive evolution (i.e., via ecological, social, neurogenic, and socio-cognitive niche construction). See for example: Nutrient–dependent / pheromone–controlled adaptive evolution: a model (published 6/14/13).

I suspect it will not be long until nutrient-dependent thermodynamic control of antibiotic resistence in E. Coli  — and perhaps in other gram negative or gram positive organisms — will be linked to cause of death by sepsis in cases where the organism more effectively thermoregulates than the invidual it kills. Unfortunately, however, I don’t know of anyone not associated with Bonnie Bassler who is examining aspects of quorum-sensing in bacteria, which will lead to incorporating nutrient-dependent pheromone-controlled reproduction of microbes in the treatment of human bacterial diseases and possibly in obesity-linked cancer et al.

About James V. Kohl 1308 Articles
James Vaughn Kohl was the first to accurately conceptualize human pheromones, and began presenting his findings to the scientific community in 1992. He continues to present to, and publish for, diverse scientific and lay audiences, while constantly monitoring the scientific presses for new information that is relevant to the development of his initial and ongoing conceptualization of human pheromones. Recently, Kohl integrated scientific evidence that pinpoints the evolved neurophysiological mechanism that links olfactory/pheromonal input to genes in hormone-secreting cells of tissue in a specific area of the brain that is primarily involved in the sensory integration of olfactory and visual input, and in the development of human sexual preferences. His award-winning 2007 article/book chapter on multisensory integration: The Mind’s Eyes: Human pheromones, neuroscience, and male sexual preferences followed an award winning 2001 publication: Human pheromones: integrating neuroendocrinology and ethology, which was coauthored by disinguished researchers from Vienna. Rarely do researchers win awards in multiple disciplines, but Kohl’s 2001 award was for neuroscience, and his 2007 “Reiss Theory” award was for social science. Kohl has worked as a medical laboratory scientist since 1974, and he has devoted more than twenty-five years to researching the relationship between the sense of smell and the development of human sexual preferences. Unlike many researchers who work with non-human subjects, medical laboratory scientists use the latest technology from many scientific disciplines to perform a variety of specialized diagnostic medical testing on people. James V. Kohl is certified with: * American Society for Clinical Pathology * American Medical Technologists James V. Kohl is a member of: * Society for Neuroscience * Society for Behavioral Neuroendocrinology * Association for Chemoreception Sciences * Society for the Scientific Study of Sexuality * International Society for Human Ethology * American Society for Clinical Laboratory Science * Mensa, the international high IQ society