1) Structure–function analysis of mouse Sry reveals dual essential roles of the C-terminal polyglutamine tract in sex determination (2014) Excerpt: “We demonstrate, using a combination of biochemical, cell-based, […]
I think what they’ve just shown us exemplifies the molecular biology of epigenetically driven adaptive evolution.
I include more information about the molecular mechanisms responsible for “…sex-specific regulation of miRNA levels that are known to influence sexually dimorphism of mRNA concentrations in the brains of mice” and in other species from microbes to man.
The ability of science writers to misrepresent what is known about cause and effect by biologists and attribute emotion to song in birds, visual input in some species, tactile input in others, and pheromones in insects defies common sense.
…this complex ability in bacteria that suppress reproduction with pheromones when insufficient nutrients are available led me to sponsor the video game “Bacillus.”
Sex on the brain: a fear of pheromones
The effect of GnRH on secretion on luteinizing hormone/follicle stimulating hormone ratios and steroidogenesis, links social odors to brain maturation across species of mammals, as well as vertebrates. Experience-dependent brain-directed behaviors should be as variable as would be expected by the association between food odors and food preferences.
The “rules” of the required molecular biology involve ligand-receptor binding. For example, from yeasts to mammals, genetic conservation of the ligand: gonadotropin releasing hormone (GnRH), and the diversification of its receptor (GnRHR) are part of the rules.
New book about pheromones