Small RNAs and nutritional epigenetics (serious humor)

Serbian government honored me by putting me on their 20 recently

Honoring Amir’s sense of humor

In the context of nutritional epigenetics and “fitness,” small RNAs are clearly the drivers of ecological adaptations, which are globally manifested in affects on behavior associated with purchasing power.

Amir Siddiqui is an expert on fitness.

However, his size does not seem to matter in the context of biologically-based cause and effect linked from nutrition to epigenetic effects on hormones that affect behavior.

At the macroscopic level, appearances can be deceiving, even the appearance of faces on currency.

Amir Siddiqui is obviously big and healthy. But he may also know what others must remember. Nutrient-dependent microRNAs are the cause of everything, including our desire to eat more cheesecake (e.g., one of Amir’s favorites).

That fact was recently supported by experimental evidence reported as “The splicing modifiers reported here are orally bioavailable compounds that penetrate into all of the tissues we tested—including brain, spinal cord, and muscle—and consequently exert their action on SMN2 splicing in all cells of the body.” See:

SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy

Few others may understand what that means, but Amir exemplifies it. Across-species examples from model organisms are required. With examples they can see, others may better understand how the decisions we make about what to eat lead to nutrient-dependent changes in the microRNA/messenger RNA balance. Those changes lead from ecological variation to the amino acid substitutions that differentiate our cell types via the conserved molecular mechanisms that differentiate all the cell types of all individuals of all species from microbes to man.

Amir has a great sense of humor and his sense of humor is also an example of how people need not know anything about biophysical constraints and molecular mechanisms to understand what is obvious about nutritional epigenetics. We are what we eat!

About James V. Kohl 1308 Articles
James Vaughn Kohl was the first to accurately conceptualize human pheromones, and began presenting his findings to the scientific community in 1992. He continues to present to, and publish for, diverse scientific and lay audiences, while constantly monitoring the scientific presses for new information that is relevant to the development of his initial and ongoing conceptualization of human pheromones. Recently, Kohl integrated scientific evidence that pinpoints the evolved neurophysiological mechanism that links olfactory/pheromonal input to genes in hormone-secreting cells of tissue in a specific area of the brain that is primarily involved in the sensory integration of olfactory and visual input, and in the development of human sexual preferences. His award-winning 2007 article/book chapter on multisensory integration: The Mind’s Eyes: Human pheromones, neuroscience, and male sexual preferences followed an award winning 2001 publication: Human pheromones: integrating neuroendocrinology and ethology, which was coauthored by disinguished researchers from Vienna. Rarely do researchers win awards in multiple disciplines, but Kohl’s 2001 award was for neuroscience, and his 2007 “Reiss Theory” award was for social science. Kohl has worked as a medical laboratory scientist since 1974, and he has devoted more than twenty-five years to researching the relationship between the sense of smell and the development of human sexual preferences. Unlike many researchers who work with non-human subjects, medical laboratory scientists use the latest technology from many scientific disciplines to perform a variety of specialized diagnostic medical testing on people. James V. Kohl is certified with: * American Society for Clinical Pathology * American Medical Technologists James V. Kohl is a member of: * Society for Neuroscience * Society for Behavioral Neuroendocrinology * Association for Chemoreception Sciences * Society for the Scientific Study of Sexuality * International Society for Human Ethology * American Society for Clinical Laboratory Science * Mensa, the international high IQ society