Signal transduction: frightfully complex

Signal Transduction: Poetry in Motion

By Ricki Lewis, PhD

Excerpt: “…the scary parts of biology were cellular respiration and the synthesis and degradation pathways of the 20 amino acids.”

My comment: There is a diagram representing the scary parts of biology in the article and an interesting poetic description of its complexity.

Unfortunately, the important parts of biology seem to have scared evolutionary theorists away from examining protein biosynthesis and degradation. Rather than learn about physics and chemistry and biology in the context of the thermodynamics and organism-level thermoregulation required for species diversity, the theorists attributed species diversity to mutations. The scary part of evolutionary theory is that some people believe in it.

It’s simple. So why not believe in it?

See for comparison: Nutrient-dependent / Pheromone-controlled adaptive evolution: (a mammalian model of thermodynamics and organism-level thermoregulation) or the 5.5 minute video.

See also the pre-publication thesis Nutrient-dependent / Pheromone–controlled thermodynamics and thermoregulation

Description

Natural selection for nutrients results in their metabolism to pheromones that control reproduction in species from microbes to man. In some species, sex differences in pheromones enable sexual selection. Using what is known about the molecular mechanisms common to species from microbes to man, an argument can be made from biological facts that extends to non-random nutrient-dependent pheromone-controlled adaptive evolution. This biological-based argument can be compared to arguments that might be made to support a cosmological / mathematical argument for random mutations theory.

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I had trouble believing in evolutionary theory because no experimental evidence suggested mutations could somehow cause species diversity. Therefore, I had the impression that the population geneticists were trying to pull a fast one, which is what Jay R. Feierman is doing each time I support my model with posts that include experimental evidence. He edits out anything that attests to the pertinence of the information.

For example 1) posted as Ecological speciation (chemistry) (2)

The role of information in cell regulation (opens full text pdf)

Excerpt: “Figure 2: Illustration of how a single coding sequence can lead to several proteins through different splicings and foldings (not necessarily confined to 2).”

My comment: Enzymatic activity is clearly involved in ecological speciation as it enables networks of glycosylation to link intercellular and intracellular signaling to morphological and behavioral phenotypes in species from microbes to man.

With Feierman’s editing, became:

The role of information in cell regulation (opens full text pdf)

Excerpt: “Figure 2: Illustration of how a single coding sequence can lead to several proteins through different splicings and foldings (not necessarily confined to 2).”

My comment: Enzymatic activity is clearly involved in . . . as it enables . . . to link . . . to . . . in species from microbes to man.

For example 2) posted as Ecological speciation (physics) (2)

Natural process – Natural selection (link opens pdf)

Excerpt: “An open system is hardly ever at a stationary state. From time to time a biological system connects to flows energy in the form of radiation from the Sun or to high-μ matter usually referred to as food.”

My comment: Natural selection of food is important to ecological speciation.

With Feierman’s editing, became: Natural process – Natural selection (link opens pdf)

Excerpt: “An open system is hardly ever at a stationary state. From time to time a biological system connects to flows energy in the form of radiation from the Sun or to high-μ matter usually referred to as food.”

My comment: Natural selection of . . . is important to . . .

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Substitution of ellipses seems childish but in addition to blocking my posts, it is what Feierman does to prevent others from grasping facts that attest to his ignorance.  He knows nothing about signal transduction, yet somehow graduated from medical school. I wonder if he knows anything that does not involve substituting theories for cumulative facts from physics, from chemistry, and from molecular biology that attest to this factd: Species diversity is nutrient-dependent and pheromone-controlled. It results from ecological variation and ecological adaptations, not mutations and evolution.

About James V. Kohl 1308 Articles
James Vaughn Kohl was the first to accurately conceptualize human pheromones, and began presenting his findings to the scientific community in 1992. He continues to present to, and publish for, diverse scientific and lay audiences, while constantly monitoring the scientific presses for new information that is relevant to the development of his initial and ongoing conceptualization of human pheromones. Recently, Kohl integrated scientific evidence that pinpoints the evolved neurophysiological mechanism that links olfactory/pheromonal input to genes in hormone-secreting cells of tissue in a specific area of the brain that is primarily involved in the sensory integration of olfactory and visual input, and in the development of human sexual preferences. His award-winning 2007 article/book chapter on multisensory integration: The Mind’s Eyes: Human pheromones, neuroscience, and male sexual preferences followed an award winning 2001 publication: Human pheromones: integrating neuroendocrinology and ethology, which was coauthored by disinguished researchers from Vienna. Rarely do researchers win awards in multiple disciplines, but Kohl’s 2001 award was for neuroscience, and his 2007 “Reiss Theory” award was for social science. Kohl has worked as a medical laboratory scientist since 1974, and he has devoted more than twenty-five years to researching the relationship between the sense of smell and the development of human sexual preferences. Unlike many researchers who work with non-human subjects, medical laboratory scientists use the latest technology from many scientific disciplines to perform a variety of specialized diagnostic medical testing on people. James V. Kohl is certified with: * American Society for Clinical Pathology * American Medical Technologists James V. Kohl is a member of: * Society for Neuroscience * Society for Behavioral Neuroendocrinology * Association for Chemoreception Sciences * Society for the Scientific Study of Sexuality * International Society for Human Ethology * American Society for Clinical Laboratory Science * Mensa, the international high IQ society