When the Sense of Smell Meets Emotion: Good and Bad

For the masses: A shot of anxiety and the world stinks September 24th, 2013 in Neuroscience.

For other researchers [subscription required] When the Sense of Smell Meets Emotion: Anxiety-State-Dependent Olfactory Processing and Neural Circuitry Adaptation

Article excerpt 1) “…recent evidence further promotes the idea that affective valence represents the dominant dimension in olfactory perception, and affective experience is the primary behavioral correlate of odorant chemical properties (Khan et al., 2007; Yeshurun and Sobel, 2010).”

Article excerpt 2) “In light of the particular relevance of olfaction in fulfilling primitive biological needs, we thus posit that olfactory perception can be largely steered by the internal state to integrate hedonic value and biological utility with basic sensory encoding (Cabanac, 1971, 1979). ”

Article excerpt 3) “…we further incorporated neural connectivity analysis (using dynamic causal modeling and psychophysiological interaction analysis; Friston et al., 1997, 2003; Gitelman et al., 2003) to unveil the neural circuitry subserving this dynamic, state-dependent process.”

My comment: Been there, done that, got the award with co-authors for article 1)  See:

1) Human Pheromones: “Integrating Neuroendocrinology and Ethology”  (cited 72 times)

2) Human pheromones and food odors: epigenetic influences on the socioaffective nature of evolved behaviors.

3) Nutrient-dependent/pheromone-controlled adaptive evolution: a model.

In mammals the “neural circuitry subserving this dynamic, state-dependent process” involves epigenetic effects of glucose uptake and epigenetic effects of pheromones on feedback loops involving gonadotropin releasing hormone (GnRH) pulse frequency.  I am certain I cannot make that clearer by adding more animal models. I am also certain others are not integrating the information about human pheromones, which is already available, to  help me present it as a model of how nutrient-stress and social-stress epigenetically effect the development of behavior in species from microbes to man via the de novo creation of olfactory receptor genes sans mutations theory. I suspect we will continue to see articles like this one and that our award-winning 2001 review will be comparatively ignored.

About James V. Kohl 1308 Articles
James Vaughn Kohl was the first to accurately conceptualize human pheromones, and began presenting his findings to the scientific community in 1992. He continues to present to, and publish for, diverse scientific and lay audiences, while constantly monitoring the scientific presses for new information that is relevant to the development of his initial and ongoing conceptualization of human pheromones. Recently, Kohl integrated scientific evidence that pinpoints the evolved neurophysiological mechanism that links olfactory/pheromonal input to genes in hormone-secreting cells of tissue in a specific area of the brain that is primarily involved in the sensory integration of olfactory and visual input, and in the development of human sexual preferences. His award-winning 2007 article/book chapter on multisensory integration: The Mind’s Eyes: Human pheromones, neuroscience, and male sexual preferences followed an award winning 2001 publication: Human pheromones: integrating neuroendocrinology and ethology, which was coauthored by disinguished researchers from Vienna. Rarely do researchers win awards in multiple disciplines, but Kohl’s 2001 award was for neuroscience, and his 2007 “Reiss Theory” award was for social science. Kohl has worked as a medical laboratory scientist since 1974, and he has devoted more than twenty-five years to researching the relationship between the sense of smell and the development of human sexual preferences. Unlike many researchers who work with non-human subjects, medical laboratory scientists use the latest technology from many scientific disciplines to perform a variety of specialized diagnostic medical testing on people. James V. Kohl is certified with: * American Society for Clinical Pathology * American Medical Technologists James V. Kohl is a member of: * Society for Neuroscience * Society for Behavioral Neuroendocrinology * Association for Chemoreception Sciences * Society for the Scientific Study of Sexuality * International Society for Human Ethology * American Society for Clinical Laboratory Science * Mensa, the international high IQ society