'Science' sans experimental proof of mutations theory

  • The Loom:

The Second Draft of the History of Science by Carl Zimmer

Excerpt: “In reality, a lot of science-related conclusions fall apart or have to be revised in later years. Science itself is starting to grapple with its flaws, with papers like “Most Published Research Findings Are False.” On the other hand, some findings gain strength over the years, as more and more evidence supports them. But those studies pile up like sand grains, and so it’s easy for journalists to overlook them, even after they’ve grown into a mountain.”

My comment: Does anyone else find it incredibly unfortunate that the History of Science includes no attempt to prove the theory of mutation-driven evolution? Thus, we have had no scientific support for a theory widely touted as support for ‘natural selection.” Indeed, mutation-driven evolution was finally refuted only yesterday (i.e., on 9/13/13) in a “Nature Communications” article titled: “An experimental test on the probability of extinction of new genetic variants.

Does anyone think that article will make a difference to evolutionary theorists, or can we all expect to continue see the propagation of ridiculous “mutation-driven evolution” in the absence of any scientific evidence for it? I hope Retro Report investigates the propagation of mutations theory in the absence of any scientific evidence for it whatsoever. That fact should be considered in the context of the History of Science, and the future of scientific pursuits.

My response to a comment in the context of “Your comment is awaiting moderation.” Here it is!

James V. Kohl
September 15, 2013

David, thanks for asking, but the article is OPEN ACCESS at https://www.nature.com/ncomms/2013/130913/ncomms3417/full/ncomms3417.html

What I’m saying is without their obfuscation: ” Our study confirms the key results from classical population genetics …” As I recall, it was studies on peppered moths and industrial melanism that led, in part, to the classical misrepresentation of predator selection as the mutation-driven force in mutation-driven evolution.

This article addresses the problem with fixation, which can be placed into the context of nutrient-dependent pheromone-controlled adaptive evolution sans mutations theory, since Darwin’s ‘conditions of life’ are nutrient-dependent and pheromone-controlled. So is the physiology of reproduction in species from microbes to man, and reproduction occurs via conserved molecular mechanisms that I have detailed with across-species examples in my model. https://www.socioaffectiveneuroscipsychol.net/index.php/snp/article/view/20553/27989

If fixation had ever been linked to mutations, but not to nutrient-dependent pheromone-controlled reproduction, the authors might have been able to continue to tout theory. Instead, they refuted mutation-driven evolution but say “…our results show that further empirical work and more theoretical models are required to accurately predict the fate of that allele over long time spans.” They indicate they are simply waiting to begin touting another theoretical model.

Why do we need more theoretical models to predict the fate of any allele over long time spans? It is perfectly clear that epigenetic effects of the sensory environment arrive via olfactory/pheromonal input and control the nutrient-dependent physiology of reproduction, which controls the fate of alleles across the evolutionary continuum?

What we need is to simply acknowledge the biological facts. The authors of this article do that, but only in passing. They say: “Our study confirms… and highlights [the fact] that the nature of adaptation can be complex.” That complexity is obviously found in the systems biology of epigenetically effected alternative splicings and fixation of alleles, which is nutrient-dependent and pheromone-controlled, which I began modeling in the early 1990′s.

Perhaps I should not have assumed that most people would know that new alleles are nutrient-dependent. That assumption led me to think it didn’t need to be proved, and that most people would accept the fact that fixation was pheromone-controlled, not mutation-driven and mutation-controlled. I was wrong to expect others would accept the facts instead of continuing to accept the theory of mutation-driven evolution.


About James V. Kohl 1308 Articles
James Vaughn Kohl was the first to accurately conceptualize human pheromones, and began presenting his findings to the scientific community in 1992. He continues to present to, and publish for, diverse scientific and lay audiences, while constantly monitoring the scientific presses for new information that is relevant to the development of his initial and ongoing conceptualization of human pheromones. Recently, Kohl integrated scientific evidence that pinpoints the evolved neurophysiological mechanism that links olfactory/pheromonal input to genes in hormone-secreting cells of tissue in a specific area of the brain that is primarily involved in the sensory integration of olfactory and visual input, and in the development of human sexual preferences. His award-winning 2007 article/book chapter on multisensory integration: The Mind’s Eyes: Human pheromones, neuroscience, and male sexual preferences followed an award winning 2001 publication: Human pheromones: integrating neuroendocrinology and ethology, which was coauthored by disinguished researchers from Vienna. Rarely do researchers win awards in multiple disciplines, but Kohl’s 2001 award was for neuroscience, and his 2007 “Reiss Theory” award was for social science. Kohl has worked as a medical laboratory scientist since 1974, and he has devoted more than twenty-five years to researching the relationship between the sense of smell and the development of human sexual preferences. Unlike many researchers who work with non-human subjects, medical laboratory scientists use the latest technology from many scientific disciplines to perform a variety of specialized diagnostic medical testing on people. James V. Kohl is certified with: * American Society for Clinical Pathology * American Medical Technologists James V. Kohl is a member of: * Society for Neuroscience * Society for Behavioral Neuroendocrinology * Association for Chemoreception Sciences * Society for the Scientific Study of Sexuality * International Society for Human Ethology * American Society for Clinical Laboratory Science * Mensa, the international high IQ society