Random mutations: nothing adaptive in 3 billion years

Review article: Human cytochromes P450 in health and disease

Daniel W. Nebert, Kjell Wikvall, and Walter L. Miller

Phil. Trans. R. Soc. B February 19, 2013 368 20120431; doi:10.1098/rstb.2012.0431

Article excerpt (with my emphasis): “With the explosion of molecular biology in the 1980s, it became clear that P450 genes existed in virtually all species—from prokaryotes to rodents and humans [14], and alignment of deduced amino acid sequences led to the first proposal of a gene superfamily nomenclature system based on evolutionary divergence [15]. This evolutionary concept also implied that all CYP genes today arose from a single ancestor, which originated probably more than 3 billion years ago.

My comment: This is an open access article. Any advocate of adaptive evolution via random mutations can attempt to find evidence that I could not find by scanning it. Please tell someone when you find it, and if you don’t tell them why you think anyone would believe in such a ridiculous theory as a basis for adaptively evolved human behavior.

About James V. Kohl 1308 Articles
James Vaughn Kohl was the first to accurately conceptualize human pheromones, and began presenting his findings to the scientific community in 1992. He continues to present to, and publish for, diverse scientific and lay audiences, while constantly monitoring the scientific presses for new information that is relevant to the development of his initial and ongoing conceptualization of human pheromones. Recently, Kohl integrated scientific evidence that pinpoints the evolved neurophysiological mechanism that links olfactory/pheromonal input to genes in hormone-secreting cells of tissue in a specific area of the brain that is primarily involved in the sensory integration of olfactory and visual input, and in the development of human sexual preferences. His award-winning 2007 article/book chapter on multisensory integration: The Mind’s Eyes: Human pheromones, neuroscience, and male sexual preferences followed an award winning 2001 publication: Human pheromones: integrating neuroendocrinology and ethology, which was coauthored by disinguished researchers from Vienna. Rarely do researchers win awards in multiple disciplines, but Kohl’s 2001 award was for neuroscience, and his 2007 “Reiss Theory” award was for social science. Kohl has worked as a medical laboratory scientist since 1974, and he has devoted more than twenty-five years to researching the relationship between the sense of smell and the development of human sexual preferences. Unlike many researchers who work with non-human subjects, medical laboratory scientists use the latest technology from many scientific disciplines to perform a variety of specialized diagnostic medical testing on people. James V. Kohl is certified with: * American Society for Clinical Pathology * American Medical Technologists James V. Kohl is a member of: * Society for Neuroscience * Society for Behavioral Neuroendocrinology * Association for Chemoreception Sciences * Society for the Scientific Study of Sexuality * International Society for Human Ethology * American Society for Clinical Laboratory Science * Mensa, the international high IQ society