Pulses of olfactory/pheromonal input

Signal and noise: Spike correlations in the olfactory system

by John Hewitt

Excerpt: “The olfactory system is not so much a hard-wired telephone network where channels can be instantaneously specified and connected by number codes, and then used to transmit further codes. There is significant overgrowth and back-pruning in olfactory networks during development, and some ongoing cell replacement, but once etched, many of its larger features remain stable.”

My comment: This comparison is meaningful: “…any message can not stand out like the clear dots and dashes of Morse code above noise, but must surf in the ocean where every wave is considered potentially meaningful.”

See for example Nurse (2008): “A metaphor here would be the use of the Morse code and the telegraph to communicate messages. Pulses of information sent along the telegraph generate a code for letters and as a consequence sentences can be communicated. This converts the same signalling pathway from a simple on/off switch to a device that can transfer, for example, the works of Shakespeare. It is likely that dynamics has been exploited more generally in the evolution of biological systems for signalling purposes, allowing the communication of more complex information.”

In mammals, breathing transmits chemical to electrical pulses (not waves) of information that allows olfactory/pheromonal input to epigenetically effect the hypothalamic secretion of gonadotropin releasing hormone (GnRH). Pulses of GnRH integrate sensory input associated with food odors and social odors called pheromones during what we were just told in the news article is a self-organized network that spontaneously emerges during prenatal and postnatal development of other sensory abilities. A self-organized network that spontaneously emerges incorporates the magic of mutation-initiated natural selection. Biological facts incorporate olfactory/pheromonal input and their epigenetic effects on RNA-directed DNA methylation and RNA-mediated amino acid substitutions that link nutrient-dependent changes in the microRNA/messenger RNA balance to the GnRH pulse and its downstream effects on other hormones that affect behavior.

The innate ability of the olfactory system to organize itself and emerge during development as the key integrator of all other sensory input (visual, tactile, auditory) results from nutrient-dependent pheromone-controlled adaptive changes in the brain and behavior of invertebrates and vertebrates.

About James V. Kohl 1308 Articles
James Vaughn Kohl was the first to accurately conceptualize human pheromones, and began presenting his findings to the scientific community in 1992. He continues to present to, and publish for, diverse scientific and lay audiences, while constantly monitoring the scientific presses for new information that is relevant to the development of his initial and ongoing conceptualization of human pheromones. Recently, Kohl integrated scientific evidence that pinpoints the evolved neurophysiological mechanism that links olfactory/pheromonal input to genes in hormone-secreting cells of tissue in a specific area of the brain that is primarily involved in the sensory integration of olfactory and visual input, and in the development of human sexual preferences. His award-winning 2007 article/book chapter on multisensory integration: The Mind’s Eyes: Human pheromones, neuroscience, and male sexual preferences followed an award winning 2001 publication: Human pheromones: integrating neuroendocrinology and ethology, which was coauthored by disinguished researchers from Vienna. Rarely do researchers win awards in multiple disciplines, but Kohl’s 2001 award was for neuroscience, and his 2007 “Reiss Theory” award was for social science. Kohl has worked as a medical laboratory scientist since 1974, and he has devoted more than twenty-five years to researching the relationship between the sense of smell and the development of human sexual preferences. Unlike many researchers who work with non-human subjects, medical laboratory scientists use the latest technology from many scientific disciplines to perform a variety of specialized diagnostic medical testing on people. James V. Kohl is certified with: * American Society for Clinical Pathology * American Medical Technologists James V. Kohl is a member of: * Society for Neuroscience * Society for Behavioral Neuroendocrinology * Association for Chemoreception Sciences * Society for the Scientific Study of Sexuality * International Society for Human Ethology * American Society for Clinical Laboratory Science * Mensa, the international high IQ society