Pheromones and neuroscience vs definitions and social science

Psychiatry in Crisis! Mental Health Director Rejects Psychiatric “Bible” and Replaces With… Nothing By John Horgan | May 4, 2013

Article excerpt: “Insel said that the NIMH will be replacing the DSM with the “Research Domain Criteria (RDoC),” which define mental disorders based not just on vague symptomology but on more specific genetic, neural and cognitive data. But then, immediately after making this dramatic announcement, Insel added that “we cannot design a system based on biomarkers or cognitive performance because we lack the data.”

Hunh? So the NIMH is replacing the DSM definitions of mental disorders, which virtually everyone agrees are profoundly flawed, with definitions that even he admits don’t exist yet!”

My comment: Note the subtle switch from “…design a system based on biomarkers…” to “…definitions that…don’t exist yet! Attention is directed away from what is known about the epigenetic effects of sensory input on the adaptively evolved gene-cell-tissue-organ-organ system pathway of mammals, and attention is refocused on definitions (i.e., meaningless classifications that someday might somehow lead to meaningful assessments). Clearly, many psychologists and psychiatrists will go kicking and screaming as they are dragged into the realm of what is currently neuroscientifically known.

What’s known includes information on biomarkers (e.g., indicators of the microRNA / messenger RNA balance required for epistasis). However, the information must be taken in the context of a model, sans definitions and dichotomies that obfuscate neuroscientifically established facts.

For example, “This model of systems biology represents the conservation of bottom-up organization and top-down activation via:
1) Nutrient stress-induced and social stress-induced intracellular changes in the microRNA  (miRNA)  /  messenger RNA  (mRNA) balance;
2) Intermolecular changes in DNA (genes) and alternative splicing;
3) Non-random experience-dependent stochastic variations in de novo gene expression and biosynthesis of odor receptors;
4) The required gene-cell-tissue-organ-organ system pathway that links sensory input directly to gene activation in neurosecretory cells and to miRNA-facilitated learning and memory in the amygdala of the adaptively evolved mammalian brain;
5) The required reciprocity that links gene expression to behavior that alters gene expression (i.e., reciprocity from genes to behavior and back) in model organisms like the honeybee.

The model is an adaptation of The Mind’s Eyes: Human pheromones, neuroscience, and male sexual preferences, which also indirectly addresses embodied cognition in the context of differences between classical conditioning of hormone-organized and hormone-activated behaviors, and contingencies of reinforcement via non-olfactory/pheromonal input. Contingencies of reinforcement do not epigenetically effect the adaptive evolution of the brain and behavior.  Olfactory/pheromonal input does epigenetically effect the adaptive evolution of the brain and behavior, which is why classical conditioning precedes operant conditioning of behavior in species from microbes to man (i.e., unless you’re a behaviorist like Glen Sizemore who cannot grasp the difference between classical (Pavlovian) conditioning, and operant conditioning.

About James V. Kohl 1308 Articles
James Vaughn Kohl was the first to accurately conceptualize human pheromones, and began presenting his findings to the scientific community in 1992. He continues to present to, and publish for, diverse scientific and lay audiences, while constantly monitoring the scientific presses for new information that is relevant to the development of his initial and ongoing conceptualization of human pheromones. Recently, Kohl integrated scientific evidence that pinpoints the evolved neurophysiological mechanism that links olfactory/pheromonal input to genes in hormone-secreting cells of tissue in a specific area of the brain that is primarily involved in the sensory integration of olfactory and visual input, and in the development of human sexual preferences. His award-winning 2007 article/book chapter on multisensory integration: The Mind’s Eyes: Human pheromones, neuroscience, and male sexual preferences followed an award winning 2001 publication: Human pheromones: integrating neuroendocrinology and ethology, which was coauthored by disinguished researchers from Vienna. Rarely do researchers win awards in multiple disciplines, but Kohl’s 2001 award was for neuroscience, and his 2007 “Reiss Theory” award was for social science. Kohl has worked as a medical laboratory scientist since 1974, and he has devoted more than twenty-five years to researching the relationship between the sense of smell and the development of human sexual preferences. Unlike many researchers who work with non-human subjects, medical laboratory scientists use the latest technology from many scientific disciplines to perform a variety of specialized diagnostic medical testing on people. James V. Kohl is certified with: * American Society for Clinical Pathology * American Medical Technologists James V. Kohl is a member of: * Society for Neuroscience * Society for Behavioral Neuroendocrinology * Association for Chemoreception Sciences * Society for the Scientific Study of Sexuality * International Society for Human Ethology * American Society for Clinical Laboratory Science * Mensa, the international high IQ society