Odors, the ectoderm, brain development, and autism

Two articles appeared on the same day in the psychiatry research yahoo group cue that link the sense of smell to atypical development via the ectoderm and neuronal “wiring” of the brain and atypical behavior in autism.

Food odor-associated atypical behavior: 1) “What happens when a child with autism refuses most foods?.” November 8th, 2013.

Pheromone-associated atypical behavior 2) “Social symptoms in autistic children may be caused by hyper-connected neurons.” November 7th, 2013.

Does anyone think in terms of systems biology instead of focusing on brain imaging and behaviors attributed to hormones downstream from THE biological core of behavior: gonadotropin releasing hormone (GnRH)?

A free “look inside” search for “Graziadei” in my 1995/2002 book (co-authored by the late Dr. Robert T. Francoeur) leads to the connection between GnRH, the olfactory bulbs, and brain development that continues to be ignored at a time when some people have obviously learned about the brain’s ectodermal origins.

Excerpted from an article posted to the cognitive neuroscience yahoo group on the same day: “Neuroscientists talk a lot about the functions of the 302, or more, neurons found in C. elegans. This worm also has some 50 glial cells, which like neurons, come from ectodermal precursor tissues.”

Shouldn’t others who are interested in psychiatry research and/or cognitive neuroscience begin to coordinate their efforts to understand disordered neuronal wiring via animal models of ecological, social, neurogenic, and socio-cognitive niche construction? The connections are as easy to make as counting from 1 to 3:  Connections: Olfactory/pheromonal input links epigenetics to adaptations via 1) the ectoderm to 2) neuronal wiring and to 3) atypical behaviors in autism. Is the problem that you must start with olfactory/pheromonal input to make the connections to adaptations and to disorders?



About James V. Kohl 1308 Articles
James Vaughn Kohl was the first to accurately conceptualize human pheromones, and began presenting his findings to the scientific community in 1992. He continues to present to, and publish for, diverse scientific and lay audiences, while constantly monitoring the scientific presses for new information that is relevant to the development of his initial and ongoing conceptualization of human pheromones. Recently, Kohl integrated scientific evidence that pinpoints the evolved neurophysiological mechanism that links olfactory/pheromonal input to genes in hormone-secreting cells of tissue in a specific area of the brain that is primarily involved in the sensory integration of olfactory and visual input, and in the development of human sexual preferences. His award-winning 2007 article/book chapter on multisensory integration: The Mind’s Eyes: Human pheromones, neuroscience, and male sexual preferences followed an award winning 2001 publication: Human pheromones: integrating neuroendocrinology and ethology, which was coauthored by disinguished researchers from Vienna. Rarely do researchers win awards in multiple disciplines, but Kohl’s 2001 award was for neuroscience, and his 2007 “Reiss Theory” award was for social science. Kohl has worked as a medical laboratory scientist since 1974, and he has devoted more than twenty-five years to researching the relationship between the sense of smell and the development of human sexual preferences. Unlike many researchers who work with non-human subjects, medical laboratory scientists use the latest technology from many scientific disciplines to perform a variety of specialized diagnostic medical testing on people. James V. Kohl is certified with: * American Society for Clinical Pathology * American Medical Technologists James V. Kohl is a member of: * Society for Neuroscience * Society for Behavioral Neuroendocrinology * Association for Chemoreception Sciences * Society for the Scientific Study of Sexuality * International Society for Human Ethology * American Society for Clinical Laboratory Science * Mensa, the international high IQ society