Nutrient-dependent pheromone-controlled fly pigmentation

Emergence and Diversification of Fly Pigmentation Through Evolution of a Gene Regulatory Module (22 March 2013)L. Arnoult et al.
Excerpt [subscription required]: Pigmentation spots on the wings of flies originate from changes at different levels of the underlying genetic hierarchy.

Conclusion with my emphasis: I may have mentioned before that “This work illustrates how a transcription factor governing several effector genes to form a morphological trait has become a privileged genetic target to modify the spatial pattern of this trait during evolution (8). A similar logic may apply generally to the numerous morphological patterns that vary spatially between related species (8–12): The emergence of these morphological novelties may result from the evolutionary modifications of effector genes, whereas their spatial diversification involves the redeployment of upstream patterning genes.

My comment: As also exemplified in the honeybee model organism; in all other invertebrates like the peppered moth; in finches and in pigeons; and in the Agouti mouse model of mammalian coloration, the Emergence and Diversification of Fly Pigmentation Through Evolution of a Gene Regulatory Module adds substantiating evidence for nutrient-dependent pheromone-controlled adaptive evolution in species from microbes to man.  I anxiously await substantiating evidence for the theory that mutations of any type (e.g., missense or nonsense) are somehow responsible for adaptive evolution, which obviously occurs at the molecular level, not at the level observed in the context of statistical analyses of observed species differences.

I continue to wonder why evolutionary theorists do not immediately respond to reports like this, as soon as they are added to the evidence against mutations theory. However, the evidence against mutations theory has become insurmountable.  Therefore, we are beginning to see the term ‘mutation’ redefined, but those re-definitions also seem to misrepresent biologically based cause and effect in the context of adaptive evolution.

This suggests to me that evolutionary theorists and other social scientists will need to learn more about the basic principles of biology and levels of biological organization if their works are to ever regain a semblance of scientific credibilty.

See also: Molecular mechanisms of ecological and social niche construction in sexual selection

About James V. Kohl 1308 Articles
James Vaughn Kohl was the first to accurately conceptualize human pheromones, and began presenting his findings to the scientific community in 1992. He continues to present to, and publish for, diverse scientific and lay audiences, while constantly monitoring the scientific presses for new information that is relevant to the development of his initial and ongoing conceptualization of human pheromones. Recently, Kohl integrated scientific evidence that pinpoints the evolved neurophysiological mechanism that links olfactory/pheromonal input to genes in hormone-secreting cells of tissue in a specific area of the brain that is primarily involved in the sensory integration of olfactory and visual input, and in the development of human sexual preferences. His award-winning 2007 article/book chapter on multisensory integration: The Mind’s Eyes: Human pheromones, neuroscience, and male sexual preferences followed an award winning 2001 publication: Human pheromones: integrating neuroendocrinology and ethology, which was coauthored by disinguished researchers from Vienna. Rarely do researchers win awards in multiple disciplines, but Kohl’s 2001 award was for neuroscience, and his 2007 “Reiss Theory” award was for social science. Kohl has worked as a medical laboratory scientist since 1974, and he has devoted more than twenty-five years to researching the relationship between the sense of smell and the development of human sexual preferences. Unlike many researchers who work with non-human subjects, medical laboratory scientists use the latest technology from many scientific disciplines to perform a variety of specialized diagnostic medical testing on people. James V. Kohl is certified with: * American Society for Clinical Pathology * American Medical Technologists James V. Kohl is a member of: * Society for Neuroscience * Society for Behavioral Neuroendocrinology * Association for Chemoreception Sciences * Society for the Scientific Study of Sexuality * International Society for Human Ethology * American Society for Clinical Laboratory Science * Mensa, the international high IQ society