RNA editing and modifications of RNAs might have favoured the evolution of the triplet genetic code from an ennuplet code
Original Research Article
Journal of Theoretical Biology, Available online 6 June 2014, Pages
Massimo Di Giulio, Marco Moracci, Beatrice Cobucci-Ponzano
Article excerpt: “The fact that today the anticodons are modified, and in particular modified by means of amino acids in a statistically significant way (Di Giulio, 1998), would make to presume in: (i) an intimate evolutionary relationship between amino acids and anticodons for the origin of the genetic code…”
My comment: That suggests the origin of the genetic code can be found in the context of ecological variation and nutrient-dependent amino acid substitutions that differentiate cell types in individuals of all species in which the physiology of reproduction is controlled by the metabolism of nutrients to pheromones.
See also: Alternative RNA Splicing in Evolution to help transition from ideas about mutations, natural selection, and the evolution of biodiversity to facts about how ecological variation in the supply of nutrients leads to ecological adaptations via conserved molecular mechanisms in species from microbes to man.
Keep in mind the unenviable position of Jay R. Feierman, who is moderator of the International Society for Human Ethology’s yahoo discussion group. Like Jon Lieff, Feierman is a psychiatrist. Unlike Jon Lieff, Feierman knows nothing about the basic principles of biology and levels of biological organization required to link the epigenetic landscape to the physical landscape of DNA in the organized genome of species from microbes to man. However, Feierman makes claims like this in reference to my published works:
Jay R. Feierman: Variation is not nutrient availability and the something that is doing the selecting is not the individual organism. A feature of an educated person is to realize what they do not know. Sadly, you don’t know that you have an incorrect understanding Darwinian biological evolution.
My comment: Feierman’s understanding of Darwinian biological evolution is what leads him to tout this ridiculous claim:
Jay R. Feierman: I am absolutely certain that if you showed this statement to any professor of biology or genetics in any accredited university anywhere in the world that 100% of them would say that “Random mutations are the substrate upon which directional natural selection acts” is a correct and true statement.
Serious scientists continue to see experimental evidence that attests to the fact that Feierman and those who still share his ridiculous ideas about biologically based cause and effect are among the uneducated “know it alls” who think their academic credentials make up for their ignorance. They are also among the academically irresponsible educators who are teaching nonsensical theories to students who may never learn about how ecological variation leads to ecological adaptations and biodiversity because they’ve been taught to believe in “Evolution for Dummies.”