Nutrient-dependent gene expression

You are what you eat — even the littlest bites: Dietary influences tied to changes in gene expression

Excerpt: “Even the most health-conscious eaters find themselves indulging in junk foods from time to time. New research raises the striking possibility that even small amounts of these occasional indulgences may produce significant changes in gene expression that could negatively impact physiology and health.”

My comment: For more detailed representations of how dietary influences cause changes in gene expression and behavior see: Nutrient-dependent / Pheromone-controlled Adaptive Evolution and Nutrient-dependent / Pheromone-controlled thermodynamics and thermoregulation. In the context of my most recently published work (Kohl, 2012), these pre-publication works link the molecular mechanisms responsible for the dietary influences in worms to nutrient-dependent pheromone-controlled adaptive evolution in species from microbes to man (sans mutations theory).

I prefer the honeybee model organism, which establishes the link from microbes to man. However, there are two advantages of the C. elegans model organism.

1) We already know differences in the behavior of nematodes are determined by nutrient-dependent rewiring of their primitive nervous system (Bumbarger, Riebesell, Rödelsperger, & Sommer, 2013). In my model this is what’s called neurogenic niche construction, which follows the requirements for ecological and social niche construction in adaptive evolution.

2) We also know that sperm-egg species incompatibilities in nematodes are associated with cysteine-to-alanine substitutions (Wilson et al., 2011). In my model these nutrient-dependent amino acid substitutions alter pheromone production, which controls reproduction. Pheromone-controlled reproduction is also required for nutrient-dependent species divergence.

About James V. Kohl 1308 Articles
James Vaughn Kohl was the first to accurately conceptualize human pheromones, and began presenting his findings to the scientific community in 1992. He continues to present to, and publish for, diverse scientific and lay audiences, while constantly monitoring the scientific presses for new information that is relevant to the development of his initial and ongoing conceptualization of human pheromones. Recently, Kohl integrated scientific evidence that pinpoints the evolved neurophysiological mechanism that links olfactory/pheromonal input to genes in hormone-secreting cells of tissue in a specific area of the brain that is primarily involved in the sensory integration of olfactory and visual input, and in the development of human sexual preferences. His award-winning 2007 article/book chapter on multisensory integration: The Mind’s Eyes: Human pheromones, neuroscience, and male sexual preferences followed an award winning 2001 publication: Human pheromones: integrating neuroendocrinology and ethology, which was coauthored by disinguished researchers from Vienna. Rarely do researchers win awards in multiple disciplines, but Kohl’s 2001 award was for neuroscience, and his 2007 “Reiss Theory” award was for social science. Kohl has worked as a medical laboratory scientist since 1974, and he has devoted more than twenty-five years to researching the relationship between the sense of smell and the development of human sexual preferences. Unlike many researchers who work with non-human subjects, medical laboratory scientists use the latest technology from many scientific disciplines to perform a variety of specialized diagnostic medical testing on people. James V. Kohl is certified with: * American Society for Clinical Pathology * American Medical Technologists James V. Kohl is a member of: * Society for Neuroscience * Society for Behavioral Neuroendocrinology * Association for Chemoreception Sciences * Society for the Scientific Study of Sexuality * International Society for Human Ethology * American Society for Clinical Laboratory Science * Mensa, the international high IQ society