Nutrient-dependent cooperation vs cannibalism (video)

Contributions of VLDLR and LRP8 in the establishment of retinogeniculate projections reported as:

Researchers find surprising relationships in brain signaling

Excerpt: “…the glycoprotein Reelin is crucial to developing healthy neural networks. Logically, taking away the two receptors that Reelin is known to act on early in the brain’s development should create the same malformations as taking away Reelin itself.  It didn’t.

My comment: Differences in glucose metabolism lead to differences in cell types via receptor-mediated behavior. Mutated receptors are ecological dead ends because perturbed protein folding does not benefit any organism of any species with differentiated cell types that are nutrient-dependent and pheromone-controlled. Nutrient-dependent cooperation is required and it is not mutation-driven.

See also:  Genetic and Neural Modularity Underlie the Evolution of Schooling Behavior in Threespine Sticklebacks reported as:

Genetics of how and why fish swim in schools: Research sheds light on complex social behavior

My comment: The link from this article to information on eye regression and schooling in blind cave fish establishes the fact that schooling is nutrient-dependent in fish. It may not depend on visual input, since changes that occur downstream of sensory input must first somehow be linked to epigenetic effects of sensory input. There is no known link between visual input and the epigenetic effects that might change genetic loci. The epigenetic landscape becomes the physical landscape of DNA in the organized genomes of species from microbes to man via olfactory/pheromonal input. That fact is consistent with experimental evidence reported as:

Excerpt: “Schooling behavior in A. mexicanus has evolved both through changes in sensory systems and through changes in genetic loci that likely act downstream of sensory inputs.”

My comment: However, it should be clear that schooling behavior has not evolved in the context of mutation-driven evolution of eyes or eye regression in cave fish. Schooling behavior is nutrient-dependent and pheromone controlled as is the social behavior of all species. That explains why “Cavefish have lost the tendency to school regardless of vision.” In their nutrient-poor environment that led to eye regression, it also led to deficits in signaling by pheromones that enables schooling.

Summary: “Genetic analysis of behavior can also reveal associations between behavior and morphological or neural phenotypes, providing insight into the proximate mechanisms that control behavior.” The proximate mechanisms that control behavior are not mutation-driven in the context of mutation-driven evolution. Proximate mechanisms are nutrient-dependent, RNA-mediated, and pheromone-controlled. They enable differences in nutrient availability to determine ecological adaptations via the pheromone-controlled physiology of reproduction in species from microbes to man.

See also: Nutrient-dependent / Pheromone-controlled adaptive evolution: (a mammalian model of thermodynamics and organism-level thermoregulation) — video excerpt.


Nutrient-dependent / Pheromone–controlled thermodynamics and thermoregulation (full text)

Nutrient-dependent / pheromone-controlled adaptive evolution (poster)


About James V. Kohl 1308 Articles
James Vaughn Kohl was the first to accurately conceptualize human pheromones, and began presenting his findings to the scientific community in 1992. He continues to present to, and publish for, diverse scientific and lay audiences, while constantly monitoring the scientific presses for new information that is relevant to the development of his initial and ongoing conceptualization of human pheromones. Recently, Kohl integrated scientific evidence that pinpoints the evolved neurophysiological mechanism that links olfactory/pheromonal input to genes in hormone-secreting cells of tissue in a specific area of the brain that is primarily involved in the sensory integration of olfactory and visual input, and in the development of human sexual preferences. His award-winning 2007 article/book chapter on multisensory integration: The Mind’s Eyes: Human pheromones, neuroscience, and male sexual preferences followed an award winning 2001 publication: Human pheromones: integrating neuroendocrinology and ethology, which was coauthored by disinguished researchers from Vienna. Rarely do researchers win awards in multiple disciplines, but Kohl’s 2001 award was for neuroscience, and his 2007 “Reiss Theory” award was for social science. Kohl has worked as a medical laboratory scientist since 1974, and he has devoted more than twenty-five years to researching the relationship between the sense of smell and the development of human sexual preferences. Unlike many researchers who work with non-human subjects, medical laboratory scientists use the latest technology from many scientific disciplines to perform a variety of specialized diagnostic medical testing on people. James V. Kohl is certified with: * American Society for Clinical Pathology * American Medical Technologists James V. Kohl is a member of: * Society for Neuroscience * Society for Behavioral Neuroendocrinology * Association for Chemoreception Sciences * Society for the Scientific Study of Sexuality * International Society for Human Ethology * American Society for Clinical Laboratory Science * Mensa, the international high IQ society