Novelty creation is not mutation-driven

Policy: Twenty tips for interpreting scientific claims

Excerpt 1: “This list will help non-scientists to interrogate advisers and to grasp the limitations of evidence….”

Excerpt 2: “…there are serious problems in the application of science to policy — from energy to health and environment to education.”

My comment: This open access publication An experimental test on the probability of extinction of new genetic variants shows non-scientists that no experimental evidence supports mutation-initiated natural selection or the theory of mutation-driven evolution.

Excerpt: “In 1927, J.B.S. Haldane reasoned that the probability of fixation of new beneficial alleles is twice their fitness effect. This result, later generalized by M. Kimura, has since become the cornerstone of modern population genetics. There is no experimental test of Haldane’s insight… Our study confirms the key results from classical population genetics and highlights that the nature of adaptation can be complex.”

My comment: It’s been 86 years since Haldane’s idea was uncritically accepted by theorists. No experimental evidence ever supported his idea. However, experimental evidence from inbred lines of nematodes (Wilson et al., 2011) can be compared to the lack of experimental evidence that might otherwise have supported Haldane’s idea. His idea can then be dismissed, or placed into the context of a model that links nutrient-dependent amino acid substitutions to adaptations in species from microbes to man.

In my model, massive neural circuit rewiring between nematodes with divergent feeding behavior: the microbivore Caenorhabditis elegans and the predatory nematode Pristionchus pacificus have been attributed to “…an evolutionary novelty unknown from C. elegans or their most recent common ancestor. P. pacificus and its relatives develop teeth-like denticles in their mouth opening and can form two distinct mouth forms (Bumbarger et al., 2013 – p 109).”

Physical evidence of this unknown evolutionary novelty exemplifies

1) de novo creation of the first tooth in the context of

2) de novo creation of olfactory receptor genes that enable nutrient uptake and

3) de novo creation of species-specific pheromones via the metabolism of nutrients.

The de novo creation of teeth is adaptive in the context of nutrient-dependent physiology of reproduction controlled by species-specific pheromones.

For contrast to novelty creation, natural selection is an evolutionary process initiated by mutation that does not have any creative power (see page 196).

Additional physical evidence for the creation of teeth that enable species to adapt to ecological niches and to form social niches that enable neurogenic niche construction (e.g. in nematodes) and socio-cognitive niche construction evidenced in invertebrates and vertebrates can be found with increasing organismal complexity. Adaptations that appeared to enable higher intelligence in some organisms seem to have ended when some people accepted Haldane’s idea of how evolution supposedly occurs outside the context of niche construction.

About James V. Kohl 1308 Articles
James Vaughn Kohl was the first to accurately conceptualize human pheromones, and began presenting his findings to the scientific community in 1992. He continues to present to, and publish for, diverse scientific and lay audiences, while constantly monitoring the scientific presses for new information that is relevant to the development of his initial and ongoing conceptualization of human pheromones. Recently, Kohl integrated scientific evidence that pinpoints the evolved neurophysiological mechanism that links olfactory/pheromonal input to genes in hormone-secreting cells of tissue in a specific area of the brain that is primarily involved in the sensory integration of olfactory and visual input, and in the development of human sexual preferences. His award-winning 2007 article/book chapter on multisensory integration: The Mind’s Eyes: Human pheromones, neuroscience, and male sexual preferences followed an award winning 2001 publication: Human pheromones: integrating neuroendocrinology and ethology, which was coauthored by disinguished researchers from Vienna. Rarely do researchers win awards in multiple disciplines, but Kohl’s 2001 award was for neuroscience, and his 2007 “Reiss Theory” award was for social science. Kohl has worked as a medical laboratory scientist since 1974, and he has devoted more than twenty-five years to researching the relationship between the sense of smell and the development of human sexual preferences. Unlike many researchers who work with non-human subjects, medical laboratory scientists use the latest technology from many scientific disciplines to perform a variety of specialized diagnostic medical testing on people. James V. Kohl is certified with: * American Society for Clinical Pathology * American Medical Technologists James V. Kohl is a member of: * Society for Neuroscience * Society for Behavioral Neuroendocrinology * Association for Chemoreception Sciences * Society for the Scientific Study of Sexuality * International Society for Human Ethology * American Society for Clinical Laboratory Science * Mensa, the international high IQ society