No mutations outside the lab

Deadly H5N1 bird flu needs just 5 mutations to spread easily in people

Excerpt 1): ” …the “bird flu” virus has yet to evolve a means of spreading easily among people.”

Excerpt 2):  “While the new study suggests the mutations needed are relatively few, it remains unclear whether they’re likely to happen outside the laboratory.”

My comment: Nutrient-dependent amino acid substitutions underlie change in the virulence of H1N1 . When the substitutions are reported in H5N1 as if they were mutations: ‘…we examine pairwise relationships between viruses and observe a correlation between amino acid mutations and antigenic distance…” biologically-based cause and effect is eliminated from any further consideration.

No mutations outside the lab occur, but laboratory researchers proceed to determine how to cause mutations. This leads to development of ineffective treatments with serious side effects.

This brings the ever-present role of evolutionary theory into the picture of molecular medicine, which requires that research proceed based on biological facts. If no mutations outside the lab occur, evolutionary theory should not be brought into the lab. Only wasted efforts from money better spent elsewhere will result from theoretical nonsense.

See also:  Tamiflu: Millions wasted on flu drug, claims major report

Excerpt: “It also claimed that the drug had a number of side-effects, including nausea, headaches, psychiatric events, kidney problems and hyperglycaemia.”

My comment: Amy Adamson and Hinissan Kohio showed that flu infection is linked to glucose metabolism in mammalian cells. That fact suggests that the side-effects of Tamiflu may be linked to altered glucose metabolism by the virus. Thus, nutritional epigenetics probably holds more promise than does evolutionary theory in the context of effective treatments with fewer reported instances of side effects.

About James V. Kohl 1308 Articles
James Vaughn Kohl was the first to accurately conceptualize human pheromones, and began presenting his findings to the scientific community in 1992. He continues to present to, and publish for, diverse scientific and lay audiences, while constantly monitoring the scientific presses for new information that is relevant to the development of his initial and ongoing conceptualization of human pheromones. Recently, Kohl integrated scientific evidence that pinpoints the evolved neurophysiological mechanism that links olfactory/pheromonal input to genes in hormone-secreting cells of tissue in a specific area of the brain that is primarily involved in the sensory integration of olfactory and visual input, and in the development of human sexual preferences. His award-winning 2007 article/book chapter on multisensory integration: The Mind’s Eyes: Human pheromones, neuroscience, and male sexual preferences followed an award winning 2001 publication: Human pheromones: integrating neuroendocrinology and ethology, which was coauthored by disinguished researchers from Vienna. Rarely do researchers win awards in multiple disciplines, but Kohl’s 2001 award was for neuroscience, and his 2007 “Reiss Theory” award was for social science. Kohl has worked as a medical laboratory scientist since 1974, and he has devoted more than twenty-five years to researching the relationship between the sense of smell and the development of human sexual preferences. Unlike many researchers who work with non-human subjects, medical laboratory scientists use the latest technology from many scientific disciplines to perform a variety of specialized diagnostic medical testing on people. James V. Kohl is certified with: * American Society for Clinical Pathology * American Medical Technologists James V. Kohl is a member of: * Society for Neuroscience * Society for Behavioral Neuroendocrinology * Association for Chemoreception Sciences * Society for the Scientific Study of Sexuality * International Society for Human Ethology * American Society for Clinical Laboratory Science * Mensa, the international high IQ society