Natural Selection and the Complexity of the Genome

Natural Selection and the Complexity of the Genome by James V. Kohl

In the Genetic Predispositions threads duplicated in Psychiatry-research and Evolutionary-psychology, there may be  a few people who have grasped the concept of adaptive evolution, which requires selection for nutrient chemicals and species-specific mixtures of chemicals called pheromones in species from microbes to man. One participant suggested that any new chemical activity in the cell must trigger a fairly powerful selective force.

Nutrient chemicals and pheromones cause receptor-mediated chemical activity in the cell that triggers natural selection, which is a powerful selective force.

Last month, another participant who has repeatedly denigrated my published work, said in a different forum: “... I envision some unconditioned stimuli to have been such a prevalent and regular feature of past environments that it makes sense to bypass the normal learning mechanism and encode the process in the DNA.

Nutrient chemicals and pheromones are prevalent unconditioned stimuli and they are also regular features of all past environments that encode normal receptor-mediated learning mechanisms in the cell via the chemical activity that causes natural selection, which is a powerful selective force.

Unfortunately, the moderator of both the psychiatry-research and evolutionary-psychology group misunderstood my conceptualization of how organisms are epigenetically fed the nutrient chemicals that enable gene duplication as a mechanism of genomic adaptation to a changing environment. He has not yet responded to my reply that “epigenetically fed” does not mean that DNA from one species becomes functional as DNA in another.  Instead, receptor-mediated ingestion of the DNA of a heterospecific becomes the nutrient chemical that enables gene duplication in conspecifics, which is required for adaptive evolution via ecological, social, neurogenic, and socio-cognitive niche construction in species from microbes to man (Kohl 2012).

As an alternative to my model,  one of the people involved in presenting the ENCODE data has said there are “random models” that may explain adaptive evolution across species. Does anyone know what he’s talking about? What “random model” helps to explain the species diversity that results from nutrient acquisition and the metabolism of nutrient chemicals to pheromones, which control reproduction in all species? If there is a “random model” that has any explanatory power not why haven’t the details of the model been offered for consideration. The “random models” proposal makes me think we will continue to be misled about the requirements for selection in the context of epigenetically altered cause and effect that involves the complexity of the genome and natural selection in all species?

About James V. Kohl 1307 Articles
James Vaughn Kohl was the first to accurately conceptualize human pheromones, and began presenting his findings to the scientific community in 1992. He continues to present to, and publish for, diverse scientific and lay audiences, while constantly monitoring the scientific presses for new information that is relevant to the development of his initial and ongoing conceptualization of human pheromones. Recently, Kohl integrated scientific evidence that pinpoints the evolved neurophysiological mechanism that links olfactory/pheromonal input to genes in hormone-secreting cells of tissue in a specific area of the brain that is primarily involved in the sensory integration of olfactory and visual input, and in the development of human sexual preferences. His award-winning 2007 article/book chapter on multisensory integration: The Mind’s Eyes: Human pheromones, neuroscience, and male sexual preferences followed an award winning 2001 publication: Human pheromones: integrating neuroendocrinology and ethology, which was coauthored by disinguished researchers from Vienna. Rarely do researchers win awards in multiple disciplines, but Kohl’s 2001 award was for neuroscience, and his 2007 “Reiss Theory” award was for social science. Kohl has worked as a medical laboratory scientist since 1974, and he has devoted more than twenty-five years to researching the relationship between the sense of smell and the development of human sexual preferences. Unlike many researchers who work with non-human subjects, medical laboratory scientists use the latest technology from many scientific disciplines to perform a variety of specialized diagnostic medical testing on people. James V. Kohl is certified with: * American Society for Clinical Pathology * American Medical Technologists James V. Kohl is a member of: * Society for Neuroscience * Society for Behavioral Neuroendocrinology * Association for Chemoreception Sciences * Society for the Scientific Study of Sexuality * International Society for Human Ethology * American Society for Clinical Laboratory Science * Mensa, the international high IQ society