Mitochondrial interactions

Excerpted from Kohl (2013)

“In flies, ecological and social niche construction can be linked to molecular-level cause and effect at the cellular and organismal levels via nutrient-dependent changes in mitochondrial tRNA and a nuclear-encoded tRNA synthetase. The enzyme enables attachment of an appropriate amino acid, which facilitates the reaction required for efficient and accurate protein synthesis (Meiklejohn et al., 2013).”

My comment: The mitochondrial interactions that enable efficient and accurate protein synthesis are central to my model. The moderator of the ISHE’s human ethology yahoo group finally realized that understanding the role of mitochondrial interactions is essential to distinguishing the differences between what is currently known about cell type differentiation and theories that ignore the mitochondrial interactions. The theories seem to claim that protein synthesis occurs via mutations that are naturally selected and result in the evolution of biodiversity. However, it’s not possible to get a theorist to say that. Even an uninformed theorist knows how ridiculous it is to claim that protein synthesis, which is nutrient-dependent, occurs in any other context outside the context of ecological variations in the supply of nutrients.

Feierman again uses a barrage of posts, a tactic common to the news media, to keep the focus on evolutionary theory — if only because accurate representations of cause and effect are extremely difficult to understand.  If you feed people too much information, they will soon make no effort to understand any of it. Instead, they will continue to believe what they’ve been taught to believe, no matter how clear it becomes to others that they have been taught to believe in pseudoscientific nonsense.

Feierman posted these four links to two different articles along with about 25 other posts today:

Shaping the dynamic mitochondrial network 
Laura L Lackner 
BMC Biology 2014, 12:35 (27 May 2014)

Mitochondrial network dynamics
Laura Lackner 
Mitochondria in eukaryotic cells form a constantly fusing and breaking network whose dynamics reflect and affect the physiological and metabolic state of the cell. In her contribution to our article series on mitochondria, Laura Lackner reviews what we know of the regulation and mechanisms of mitochondrial network dynamics.

Mitochondria as signaling organelles 
Navdeep S Chandel 
BMC Biology 2014, 12:34 (27 May 2014)

Many modes of signalling by mitochondria
Navdeep Chandel 
In his contribution to our series on the biology of mitochondria, Navdeep Chandel tracks the emergence of mitochondria as signalling organelles, and the new directions in which research on mitochondrial signalling is leading.

The challenge is to try to make any sense at all of Feierman’s posts. It may also be challenging to attempt to understand how nutrient-dependent changes in mitochondrial tRNA and a nuclear-encoded tRNA synthetase. enable appropriate amino acid substitutions that facilitate efficient and accurate protein synthesis. However, there’s a model for that. It can be compared to Feierman’s opinion:

I am absolutely certain that if you showed this statement to any professor of biology or genetics in any accredited university anywhere in the world that 100% of them would say that “Random mutations are the substrate upon which directional natural selection acts” is a correct and true statement.




About James V. Kohl 1308 Articles
James Vaughn Kohl was the first to accurately conceptualize human pheromones, and began presenting his findings to the scientific community in 1992. He continues to present to, and publish for, diverse scientific and lay audiences, while constantly monitoring the scientific presses for new information that is relevant to the development of his initial and ongoing conceptualization of human pheromones. Recently, Kohl integrated scientific evidence that pinpoints the evolved neurophysiological mechanism that links olfactory/pheromonal input to genes in hormone-secreting cells of tissue in a specific area of the brain that is primarily involved in the sensory integration of olfactory and visual input, and in the development of human sexual preferences. His award-winning 2007 article/book chapter on multisensory integration: The Mind’s Eyes: Human pheromones, neuroscience, and male sexual preferences followed an award winning 2001 publication: Human pheromones: integrating neuroendocrinology and ethology, which was coauthored by disinguished researchers from Vienna. Rarely do researchers win awards in multiple disciplines, but Kohl’s 2001 award was for neuroscience, and his 2007 “Reiss Theory” award was for social science. Kohl has worked as a medical laboratory scientist since 1974, and he has devoted more than twenty-five years to researching the relationship between the sense of smell and the development of human sexual preferences. Unlike many researchers who work with non-human subjects, medical laboratory scientists use the latest technology from many scientific disciplines to perform a variety of specialized diagnostic medical testing on people. James V. Kohl is certified with: * American Society for Clinical Pathology * American Medical Technologists James V. Kohl is a member of: * Society for Neuroscience * Society for Behavioral Neuroendocrinology * Association for Chemoreception Sciences * Society for the Scientific Study of Sexuality * International Society for Human Ethology * American Society for Clinical Laboratory Science * Mensa, the international high IQ society