Human Pheromones: extremely technical representation of the concept

For those interested in highly technical representations of the concept of human pheromones:

Population Genomics of Early Events in the Ecological Differentiation of Bacteria

  • B. Jesse Shapiro,
  • Jonathan Friedman,
  • Otto X. Cordero,
  • Sarah P. Preheim,
  • Sonia C. Timberlake,
  • Gitta Szabó,
  • Martin F. Polz,
  • and Eric J. Alm

Science 6 April 2012: 336 (6077), 4851. [DOI:10.1126/science.1218198]

Abstract (subscription required to read the full text of this article)

Genetic exchange is common among bacteria, but its effect on population diversity during ecological differentiation remains controversial. A fundamental question is whether advantageous mutations lead to selection of clonal genomes or, as in sexual eukaryotes, sweep through populations on their own. Here, we show that in two recently diverged populations of ocean bacteria, ecological differentiation has occurred akin to a sexual mechanism: A few genome regions have swept through subpopulations in a habitat-specific manner, accompanied by gradual separation of gene pools as evidenced by increased habitat specificity of the most recent recombinations. These findings reconcile previous, seemingly contradictory empirical observations of the genetic structure of bacterial populations and point to a more unified process of differentiation in bacteria and sexual eukaryotes than previously thought.


My comment on the full text of this article is apparently not going to be published so I will add it here:

Isn’t it most likely that nutrient chemicals establish the ecological niche of different bacterial species and that nutrient calibrated receptor-mediated  events link the metabolism of nutrients to pheromones that standardize and  control speciation (e.g., via changes in intracellular signaling and  stochastic gene expression)? This would link microbes to man via the origins of the olfactory and immune systems with a clear evolutionary trail that can be followed by the development of olfaction and odor receptors. I’m having difficulty opening up a dialogue in this regard, despite my publication history, and current position in microbiology. Can anyone advise me on errors in logic, basic principles of biology, or levels of biological organization
in this regard?


About James V. Kohl 1308 Articles
James Vaughn Kohl was the first to accurately conceptualize human pheromones, and began presenting his findings to the scientific community in 1992. He continues to present to, and publish for, diverse scientific and lay audiences, while constantly monitoring the scientific presses for new information that is relevant to the development of his initial and ongoing conceptualization of human pheromones. Recently, Kohl integrated scientific evidence that pinpoints the evolved neurophysiological mechanism that links olfactory/pheromonal input to genes in hormone-secreting cells of tissue in a specific area of the brain that is primarily involved in the sensory integration of olfactory and visual input, and in the development of human sexual preferences. His award-winning 2007 article/book chapter on multisensory integration: The Mind’s Eyes: Human pheromones, neuroscience, and male sexual preferences followed an award winning 2001 publication: Human pheromones: integrating neuroendocrinology and ethology, which was coauthored by disinguished researchers from Vienna. Rarely do researchers win awards in multiple disciplines, but Kohl’s 2001 award was for neuroscience, and his 2007 “Reiss Theory” award was for social science. Kohl has worked as a medical laboratory scientist since 1974, and he has devoted more than twenty-five years to researching the relationship between the sense of smell and the development of human sexual preferences. Unlike many researchers who work with non-human subjects, medical laboratory scientists use the latest technology from many scientific disciplines to perform a variety of specialized diagnostic medical testing on people. James V. Kohl is certified with: * American Society for Clinical Pathology * American Medical Technologists James V. Kohl is a member of: * Society for Neuroscience * Society for Behavioral Neuroendocrinology * Association for Chemoreception Sciences * Society for the Scientific Study of Sexuality * International Society for Human Ethology * American Society for Clinical Laboratory Science * Mensa, the international high IQ society