Hermetic Principles: experimental evidence backs a unique approach (2)

See the discussion section of A radical new holistic view of health based on cooperation and disease based on competition

Mention of a Hermetic principle: “Whatever is below is similar to that which is above” led me to information about the Hermetic Principle of Cause and Effect, which seems pertinent to include in the context of health based on cooperation and disease based on competition.

My comment: Is the Hermetic Principle of Cause and Effect more commonly known as “x” acts on “y” and causes “z”? If so, in the context of healthy adaptive evolution, “x” is cooperation in nutrient acquisition that causes beneficial effects in populations where “y” is the altered thermodynamics of intercellular signaling that leads to intranuclear interactions and nutrient-dependent stochastic de novo creation of olfactory receptor genes.

Randomness is eliminated because the metabolism of nutrients to species-specific pheromones that control reproduction leads to “z” via competition for well-nourished mates in species that sexually reproduce. A well-nourished mate is one who has the enhanced nutrient-dependent ability to thermoregulate the thermodynamics of its organism-level existence. Organism-level thermoregulation is a function of olfactory and immune system integration (i.e., self vs non-self recognition) via epigenetic effects of the sensory environment on conserved molecular mechanisms in species from microbes to man.  In yeasts, for example, at the advent of sexual reproduction, we find that it is nutrient-dependent and pheromone-controlled.

Conserved molecular mechanisms enable nutrient-dependent pheromone-controlled alternative splicings via fixation of new alleles in all species. Healthy nutrient-dependent amino acid substitutions, which are required for adaptive evolution, result from epigenetic effects of food “odors” on experience-dependent receptor-mediated behavior. See for review: Nutrient-dependent/pheromone-controlled adaptive evolution: a model.

Mutations perturb health by altering healthy receptor function and randomly disabling nutrient-dependent control of stochastic gene expression by pheromones that signal reproductive fitness and control reproduction, thus controlling the population-wide spread of mutations. That’s why mutations are not not beneficial, not fixed, and are associated with diseases and disorders, but not healthy “adaptive” evolution.

It would be great to see cause and effect incorporated into medical models of health-based cooperation and mutation-driven disease-based competition for nutrients. But first, given my history of publications that have explained the conserved molecular mechanisms, we may need to dispense with the ridiculous theory of mutation-driven evolution. It serves only to confuse people about cause and effect via misrepresentations of what mutations may do, which they cannot do because they do not enable fixation.  See, for review: An experimental test on the probability of extinction of new genetic variants.

About James V. Kohl 1308 Articles
James Vaughn Kohl was the first to accurately conceptualize human pheromones, and began presenting his findings to the scientific community in 1992. He continues to present to, and publish for, diverse scientific and lay audiences, while constantly monitoring the scientific presses for new information that is relevant to the development of his initial and ongoing conceptualization of human pheromones. Recently, Kohl integrated scientific evidence that pinpoints the evolved neurophysiological mechanism that links olfactory/pheromonal input to genes in hormone-secreting cells of tissue in a specific area of the brain that is primarily involved in the sensory integration of olfactory and visual input, and in the development of human sexual preferences. His award-winning 2007 article/book chapter on multisensory integration: The Mind’s Eyes: Human pheromones, neuroscience, and male sexual preferences followed an award winning 2001 publication: Human pheromones: integrating neuroendocrinology and ethology, which was coauthored by disinguished researchers from Vienna. Rarely do researchers win awards in multiple disciplines, but Kohl’s 2001 award was for neuroscience, and his 2007 “Reiss Theory” award was for social science. Kohl has worked as a medical laboratory scientist since 1974, and he has devoted more than twenty-five years to researching the relationship between the sense of smell and the development of human sexual preferences. Unlike many researchers who work with non-human subjects, medical laboratory scientists use the latest technology from many scientific disciplines to perform a variety of specialized diagnostic medical testing on people. James V. Kohl is certified with: * American Society for Clinical Pathology * American Medical Technologists James V. Kohl is a member of: * Society for Neuroscience * Society for Behavioral Neuroendocrinology * Association for Chemoreception Sciences * Society for the Scientific Study of Sexuality * International Society for Human Ethology * American Society for Clinical Laboratory Science * Mensa, the international high IQ society