Genes from nowhere: adaptive evolution comment to New Scientist

Genes from nowhere: Orphans with a surprising story

  • 16 January 2013 by Helen Pilcher (SUBSCRIPTION REQUIRED)

Excerpt: “The upshot is that the chances of random mutations turning a bit of junk DNA into a new gene seem infinitesimally small. As the French biologist François Jacob famously wrote 35 years ago, “the probability that a functional protein would appear de novo by random association of amino acids is practically zero”.”

My comment: De novo gene expression is obviously nutrient chemical-dependent  — as is life in all organisms. The metabolism of nutrients to species-specific pheromones controls reproduction in species from microbes to man (as best exemplified in the honeybee model organism).

What is so difficult to grasp about the epigenetic effects of nutrients and pheromones in the context of how the epigenetic landscape becomes the physical landscape via chromatin remodeling? “Olfaction and odor receptors provide a clear evolutionary trail that can be followed from unicellular organisms to insects to humans.”

Chemical ecology enables adaptive evolution via ecological, social, neurogenic, and socio-cognitive niche construction. Once the ridiculous theory that random mutations cause adaptive evolution is eliminated from consideration (as has happened here), how can anyone not grasp the fact that adaptive evolution is epigenetically driven by nutrients and controlled by their metabolism to pheromones?

It should not take a more thorough explanation of the microRNA / messenger RNA balance to move forward in this context. Should it? Most people would not understand the molecular biology, anyway. But who doesn’t understand the role of nutrition and nutrient-dependent production of species-specific pheromones that control reproduction? There’s no other model for that, with or without details of the molecular mechanisms common to all species!

Kohl, J.V. (2012) Human pheromones and food odors: epigenetic influences on the socioaffective nature of evolved behaviors. Socioaffective Neuroscience & Psychology, 2: 17338. DOI: 10.3402/snp.v2i0.17338.

About James V. Kohl 1308 Articles
James Vaughn Kohl was the first to accurately conceptualize human pheromones, and began presenting his findings to the scientific community in 1992. He continues to present to, and publish for, diverse scientific and lay audiences, while constantly monitoring the scientific presses for new information that is relevant to the development of his initial and ongoing conceptualization of human pheromones. Recently, Kohl integrated scientific evidence that pinpoints the evolved neurophysiological mechanism that links olfactory/pheromonal input to genes in hormone-secreting cells of tissue in a specific area of the brain that is primarily involved in the sensory integration of olfactory and visual input, and in the development of human sexual preferences. His award-winning 2007 article/book chapter on multisensory integration: The Mind’s Eyes: Human pheromones, neuroscience, and male sexual preferences followed an award winning 2001 publication: Human pheromones: integrating neuroendocrinology and ethology, which was coauthored by disinguished researchers from Vienna. Rarely do researchers win awards in multiple disciplines, but Kohl’s 2001 award was for neuroscience, and his 2007 “Reiss Theory” award was for social science. Kohl has worked as a medical laboratory scientist since 1974, and he has devoted more than twenty-five years to researching the relationship between the sense of smell and the development of human sexual preferences. Unlike many researchers who work with non-human subjects, medical laboratory scientists use the latest technology from many scientific disciplines to perform a variety of specialized diagnostic medical testing on people. James V. Kohl is certified with: * American Society for Clinical Pathology * American Medical Technologists James V. Kohl is a member of: * Society for Neuroscience * Society for Behavioral Neuroendocrinology * Association for Chemoreception Sciences * Society for the Scientific Study of Sexuality * International Society for Human Ethology * American Society for Clinical Laboratory Science * Mensa, the international high IQ society