Experience, odors, hormones, and neural influences on behavior

Food for Thought: Hormonal, Experiential, and Neural Influences on Feeding and Obesity

“Epigenetic mechanisms (i.e., DNA methylation, histone modifications, microRNAs) have emerged as dynamic pathways through which environmental experiences can come to be integrated within our biology, leading to variation in neurobiology, behavior, and health (Jirtle and Skinner, 2007; Champagne, 2010). Thus, in contrast to the historical view that epigenetic variation is erased at the time of fertilization, there appears to be transmission of this variation to subsequent generations…”

Anyone still touting random mutations as if they ever could possibly have ever been the substrates on which directional natural selection acts, which they are not, has remained free to provide evidence for that assertion until now. They will now be forced to provide experimental evidence for that continued assertion. Clearly, that assertion is false; there has never been experimental evidence to support it; and claims made without experimental evidence are foolish claims.

Unfortunately, the full text of this published work is no longer available from “Advances in Human Behavior and Evolution.” However, part of it is linked below, and I have posted the abstract here.

Human Pheromones: Mammalian Olfactory, Genetic, Neuronal, Hormonal, and Behavioral Reciprocity and, Human Sexuality

Abstract: Pheromonally induced alterations in gonadotropin releasing hormone (GnRH) pulsatility allow for a lifelong causal linkage among olfaction, neurotransmission, autonomic responses, luteinizing hormone/follicle stimulating hormone ratios, steroidogenesis, neurotransmission, and hormonally induced behavioral changes. This integrative multidisciplinary literature review supports the following neuroendocrine sequence: The early prenatal migration of GnRH neurosecretory neurons establishes neural substrates. These substrates appear to enable human olfactory pathways to exhibit sexually dimorphic specificity to social environmental chemical stimuli and to exhibit the ability to transduce these chemical signals or pheromones. Human pheromones thereby appear to activate genes in GnRH neurons and to influence GnRH pulsatility and gonadotropin secretion.


About James V. Kohl 1308 Articles
James Vaughn Kohl was the first to accurately conceptualize human pheromones, and began presenting his findings to the scientific community in 1992. He continues to present to, and publish for, diverse scientific and lay audiences, while constantly monitoring the scientific presses for new information that is relevant to the development of his initial and ongoing conceptualization of human pheromones. Recently, Kohl integrated scientific evidence that pinpoints the evolved neurophysiological mechanism that links olfactory/pheromonal input to genes in hormone-secreting cells of tissue in a specific area of the brain that is primarily involved in the sensory integration of olfactory and visual input, and in the development of human sexual preferences. His award-winning 2007 article/book chapter on multisensory integration: The Mind’s Eyes: Human pheromones, neuroscience, and male sexual preferences followed an award winning 2001 publication: Human pheromones: integrating neuroendocrinology and ethology, which was coauthored by disinguished researchers from Vienna. Rarely do researchers win awards in multiple disciplines, but Kohl’s 2001 award was for neuroscience, and his 2007 “Reiss Theory” award was for social science. Kohl has worked as a medical laboratory scientist since 1974, and he has devoted more than twenty-five years to researching the relationship between the sense of smell and the development of human sexual preferences. Unlike many researchers who work with non-human subjects, medical laboratory scientists use the latest technology from many scientific disciplines to perform a variety of specialized diagnostic medical testing on people. James V. Kohl is certified with: * American Society for Clinical Pathology * American Medical Technologists James V. Kohl is a member of: * Society for Neuroscience * Society for Behavioral Neuroendocrinology * Association for Chemoreception Sciences * Society for the Scientific Study of Sexuality * International Society for Human Ethology * American Society for Clinical Laboratory Science * Mensa, the international high IQ society