Epistasis: Epigenetic effects of nutrient chemicals and their metabolism to pheromones

The genetics of molecular evolution.  November 6th, 2012.

Excerpt: “The study of the factors determining the tempo and mode of molecular evolution continues to be at the forefront of evolutionary biology. Many studies have focused on the role of selection versus genetic drift in the fixation of amino-acid substitutions. Scientists are now certain that both, selection and genetic drift, contribute to a substantial fraction of all amino-acid substitutions in the course of evolution.”

My comment: Isn’t the balance of microRNA and messenger RNA responsible for the stochastic gene expression required for adaptive evolution via ecological, social, neurogenic, and socio-cognitive niche construction? If so, epistasis is achieved via the epigenetic effects of nutrient chemicals, which are balanced by the epigenetic effects of their metabolism to pheromones that control reproduction in species from microbes to man.

The likelihood that individuals eat to survive and that their pheromones control reproduction of their species is not a novel idea. But perhaps I’ve made it too complicated in my most recently published work. Should I have titled it: Epistasis, instead of Human pheromones and food odors: epigenetic influences on the socioaffective nature of evolved behaviors. Socioaffective Neuroscience & Psychology, 2: 17338.

About James V. Kohl 1307 Articles
James Vaughn Kohl was the first to accurately conceptualize human pheromones, and began presenting his findings to the scientific community in 1992. He continues to present to, and publish for, diverse scientific and lay audiences, while constantly monitoring the scientific presses for new information that is relevant to the development of his initial and ongoing conceptualization of human pheromones. Recently, Kohl integrated scientific evidence that pinpoints the evolved neurophysiological mechanism that links olfactory/pheromonal input to genes in hormone-secreting cells of tissue in a specific area of the brain that is primarily involved in the sensory integration of olfactory and visual input, and in the development of human sexual preferences. His award-winning 2007 article/book chapter on multisensory integration: The Mind’s Eyes: Human pheromones, neuroscience, and male sexual preferences followed an award winning 2001 publication: Human pheromones: integrating neuroendocrinology and ethology, which was coauthored by disinguished researchers from Vienna. Rarely do researchers win awards in multiple disciplines, but Kohl’s 2001 award was for neuroscience, and his 2007 “Reiss Theory” award was for social science. Kohl has worked as a medical laboratory scientist since 1974, and he has devoted more than twenty-five years to researching the relationship between the sense of smell and the development of human sexual preferences. Unlike many researchers who work with non-human subjects, medical laboratory scientists use the latest technology from many scientific disciplines to perform a variety of specialized diagnostic medical testing on people. James V. Kohl is certified with: * American Society for Clinical Pathology * American Medical Technologists James V. Kohl is a member of: * Society for Neuroscience * Society for Behavioral Neuroendocrinology * Association for Chemoreception Sciences * Society for the Scientific Study of Sexuality * International Society for Human Ethology * American Society for Clinical Laboratory Science * Mensa, the international high IQ society