Epigenetically-effected sexual orientation

The neurobiology and psychology of pedophilia: recent advances and challenges

Excerpt:

Support for a neurodevelopmental pathway comes from research investigating epigenetic dysregulation of sexual development in general, physical characteristics, and functional as well as structural brain differences in pedophilia.

From Fertilization to Adult Sexual Behavior

Excerpt:

…if specific genes or genomic regions are found to be primary determinants of sexual orientations, upstream and downstream genes are likely also to play crucial roles. And these multigene interrelationships will have profound impact upon phenotypes and judgments derived therefrom. Parenthetically it is interesting to note even the yeast Saccharomyces cerevisiae has a gene-based equivalent of sexual orientation (i.e., a-factor and alpha-factor physiologies). These differences arise from different epigenetic modifications of an otherwise identical MAT locus (Runge and Zakian, 1996; Wu and Haber, 1995).

Experimental evidence continues to show that the epigenetically altered microRNA/messenger RNA balance determined the cell types of all cells in all tissues in all individuals of all living genera. Sexologists have ignored virtually all that experimental evidence and continued to place their findings into the context of visual input and brain imaging.

Despite my award winning review, The Mind’s Eyes: Human pheromones, neuroscience, and male sexual preferences, and my 2007 Plenary session at the annual meeting of the Society for the Scientific Study of Sexuality, the impact of this large group of primarily “social scientists” has limited the impact of accurate information about the neurobiology and psychology that has steadily come forward from organizations like the RNA Society.

Eventually, all serious scientists will ask the social scientists, how could you ignore all the experimental evidence that links cell type differentiation to the molecular epigenetics of behavioral development, when only one amino acid substitution clearly affects the life history transitions from adolescence to adulthood?

Oppositional COMT Val158Met effects on resting state functional connectivity in adolescents and adults

See also: Interview with Dr. Jaak Panksepp, Author of Affective Neuroscience: The Foundations of Human and Animal Emotions

Excerpt:

My feeling is that the social brain has many levels. If you don’t understand the foundational level, then you can do brain imaging until you’re blue in the face, but you still will not understand the process at a deep causal level.

About James V. Kohl 1307 Articles
James Vaughn Kohl was the first to accurately conceptualize human pheromones, and began presenting his findings to the scientific community in 1992. He continues to present to, and publish for, diverse scientific and lay audiences, while constantly monitoring the scientific presses for new information that is relevant to the development of his initial and ongoing conceptualization of human pheromones. Recently, Kohl integrated scientific evidence that pinpoints the evolved neurophysiological mechanism that links olfactory/pheromonal input to genes in hormone-secreting cells of tissue in a specific area of the brain that is primarily involved in the sensory integration of olfactory and visual input, and in the development of human sexual preferences. His award-winning 2007 article/book chapter on multisensory integration: The Mind’s Eyes: Human pheromones, neuroscience, and male sexual preferences followed an award winning 2001 publication: Human pheromones: integrating neuroendocrinology and ethology, which was coauthored by disinguished researchers from Vienna. Rarely do researchers win awards in multiple disciplines, but Kohl’s 2001 award was for neuroscience, and his 2007 “Reiss Theory” award was for social science. Kohl has worked as a medical laboratory scientist since 1974, and he has devoted more than twenty-five years to researching the relationship between the sense of smell and the development of human sexual preferences. Unlike many researchers who work with non-human subjects, medical laboratory scientists use the latest technology from many scientific disciplines to perform a variety of specialized diagnostic medical testing on people. James V. Kohl is certified with: * American Society for Clinical Pathology * American Medical Technologists James V. Kohl is a member of: * Society for Neuroscience * Society for Behavioral Neuroendocrinology * Association for Chemoreception Sciences * Society for the Scientific Study of Sexuality * International Society for Human Ethology * American Society for Clinical Laboratory Science * Mensa, the international high IQ society