Epigenetic effects vs mutations

Getting to know you: Directed evolution allows pathobiology-free antibody determination

This article links self vs non-self identification via the conserved molecular mechanisms of gut microbes (like E. coli) to disorders of the immune system that have typically been attributed to mutation-initiated natural selection. No experimental evidence supports claims associated with mutation-driven evolution.

Excerpt: “Precise detection of specific antibodies is fundamental in diagnosing a wide range of diseases – and testing for antibodies using known”

My comment: Reports like this one exemplify why others should already have learned that adaptive evolution is nutrient-dependent and pheromone-controlled. Unfortunately, theorists have been convinced they should ignore accurate claims and simply accept — with no experimental evidence to support them — the claims based on mutation-driven evolution.

Those claims have prevented scientific progress for several decades, and they may keep theorists from making scientific progress in the future. At some point, biologists will make no further attempts to explain the biological basis of adaptations to anyone who believes that theory trumps what is already known about cause and effect.

For contrast, the method of disease detection this article details will obviously be useful “…to reveal previously unknown environmental factors involved in disease.”

That’s because the method incorporates what is currently known about biologically-based adaptations and does not include anything that theorists attribute to mutations and disease.

Mutations and disease are not adaptive, which explains why there is no mention of mutations in the entirety of this excellent report. Environmental factors involved in disease act via epigenetic effects that may be linked to mutations when the mutations are not eliminated by nutrient-dependent pheromone-controlled natural genetic variation.

About James V. Kohl 1308 Articles
James Vaughn Kohl was the first to accurately conceptualize human pheromones, and began presenting his findings to the scientific community in 1992. He continues to present to, and publish for, diverse scientific and lay audiences, while constantly monitoring the scientific presses for new information that is relevant to the development of his initial and ongoing conceptualization of human pheromones. Recently, Kohl integrated scientific evidence that pinpoints the evolved neurophysiological mechanism that links olfactory/pheromonal input to genes in hormone-secreting cells of tissue in a specific area of the brain that is primarily involved in the sensory integration of olfactory and visual input, and in the development of human sexual preferences. His award-winning 2007 article/book chapter on multisensory integration: The Mind’s Eyes: Human pheromones, neuroscience, and male sexual preferences followed an award winning 2001 publication: Human pheromones: integrating neuroendocrinology and ethology, which was coauthored by disinguished researchers from Vienna. Rarely do researchers win awards in multiple disciplines, but Kohl’s 2001 award was for neuroscience, and his 2007 “Reiss Theory” award was for social science. Kohl has worked as a medical laboratory scientist since 1974, and he has devoted more than twenty-five years to researching the relationship between the sense of smell and the development of human sexual preferences. Unlike many researchers who work with non-human subjects, medical laboratory scientists use the latest technology from many scientific disciplines to perform a variety of specialized diagnostic medical testing on people. James V. Kohl is certified with: * American Society for Clinical Pathology * American Medical Technologists James V. Kohl is a member of: * Society for Neuroscience * Society for Behavioral Neuroendocrinology * Association for Chemoreception Sciences * Society for the Scientific Study of Sexuality * International Society for Human Ethology * American Society for Clinical Laboratory Science * Mensa, the international high IQ society