Epigenetic effects of viruses on cellular homeostasis (2)

February 4, 2015 James V. Kohl RNA 0

TSLive: The Enemy Within (video)

How viruses wield tiny molecules of RNA to help them persist in our bodies for years, decades, and sometimes an entire life span

By The Scientist Staff | February 1, 2015

This brief video (below) packages an exceptional amount of information. In less than 2 minutes, it links the epigenetic effects of viral microRNAs to the differentiation of all cell types in all individuals of all species via the innate ability of immune system regulation to control their proliferation.

Thermodynamic cycles of protein biosynthesis and degradation link changes in the microRNA/messenger RNA balance to protein biosynthesis and degradation. The chemistry of protein biosynthesis is nutrient-dependent, and RNA-mediated amino acid substitutions stabilize the DNA in organized genomes.

Stability of DNA is perturbed by nutrient-stress and social stress. Stress also may cause loss of function mutations that link perturbed protein folding to physiopathology.

Virus-induced changes in the microRNA/messenger RNA balance may be beneficial if they enable nutrient-dependent pheromone-controlled fixation of amino acid substitutions. However, theorists typically confuse what happens in healthy organisms with what happens in cases where viruses cause physiopathology.

Short-term physiopathology is obvious within the context of rhinoviruses and other viruses that cause treatable symptoms. Long-term changes in the microRNA/messenger RNA balance lead to diseases and disorders when the immune system is stressed by the lack of essential nutrients or lack of social contact or changes during aging that alter the ability of the innate immune system to respond with maximal efficiency.

The fine-tuning of the microRNA/messenger RNA balance is required for health and reproductive fitness and it is essential to the development of morphological and behavioral phenotypes in species from microbes to man. See also: Nutrient-dependent pheromone-controlled ecological adaptations: from atoms to ecosystems.

 

See also:

Epigenetic effects of viruses on cellular homeostasis

Additional content is posted here and can be found via a search for “viral microRNA “

About James V. Kohl 1308 Articles
James Vaughn Kohl was the first to accurately conceptualize human pheromones, and began presenting his findings to the scientific community in 1992. He continues to present to, and publish for, diverse scientific and lay audiences, while constantly monitoring the scientific presses for new information that is relevant to the development of his initial and ongoing conceptualization of human pheromones. Recently, Kohl integrated scientific evidence that pinpoints the evolved neurophysiological mechanism that links olfactory/pheromonal input to genes in hormone-secreting cells of tissue in a specific area of the brain that is primarily involved in the sensory integration of olfactory and visual input, and in the development of human sexual preferences. His award-winning 2007 article/book chapter on multisensory integration: The Mind’s Eyes: Human pheromones, neuroscience, and male sexual preferences followed an award winning 2001 publication: Human pheromones: integrating neuroendocrinology and ethology, which was coauthored by disinguished researchers from Vienna. Rarely do researchers win awards in multiple disciplines, but Kohl’s 2001 award was for neuroscience, and his 2007 “Reiss Theory” award was for social science. Kohl has worked as a medical laboratory scientist since 1974, and he has devoted more than twenty-five years to researching the relationship between the sense of smell and the development of human sexual preferences. Unlike many researchers who work with non-human subjects, medical laboratory scientists use the latest technology from many scientific disciplines to perform a variety of specialized diagnostic medical testing on people. James V. Kohl is certified with: * American Society for Clinical Pathology * American Medical Technologists James V. Kohl is a member of: * Society for Neuroscience * Society for Behavioral Neuroendocrinology * Association for Chemoreception Sciences * Society for the Scientific Study of Sexuality * International Society for Human Ethology * American Society for Clinical Laboratory Science * Mensa, the international high IQ society