Embracing galaxy-wide, cellular, and brain complexity

September 24, 2012 — The Daily Galaxy via Allen Institute for Brain Science

“More Complex Than a Galaxy” –New Insights Into the Enormous Biochemical Complexity of the Human Brain

Excerpt: “This study demonstrates the value of a global analysis of gene expression throughout the entire brain and has implications for understanding brain function, development, evolution and disease,” said Ed Lein, Ph.D., Associate Investigator at the Allen Institute for Brain Science and co-lead author on the paper.

My comment: Nutrient chemicals determine similarities in brain development. The nutrients are metabolized to species-specific mixtures of pheromones that determine individual differences in the development of adaptively evolved personalities and cognitive talents (via ecological, social, neurogenic, and socio-cognitive niche construction).

The epigenetic effects of nutrient chemicals and pheromones on genetically predisposed intracellular signaling and stochastic gene expression have been modeled in the honeybee model organism, which extends to humans the concept of the epigenetic tweaking of immense gene networks in superorganisms that solve problems through the exchange and the selective cancellation and modification of signals.

It is now clear how an environmental drive evolved from that of food ingestion in unicellular organisms to that of socialization in insects. It is also clear that, in mammals, food odors and pheromones cause changes in hormones that have developmental affects on behavior in nutrient-dependent, reproductively fit individuals across species of vertebrates.

The developmental affects on our behavior are manifestations of the epigenetic effects of nutrient chemicals and pheromones on hormones and brain development. If we eliminate consideration for the epigenetic effects of human pheromones, we have an explanation for nutrient chemical-dependent brain similarities, but no explanation for differences in behavior that are pheromone-dependent in all other species.

The differences in behavior are species specific and so are pheromones. What does that tell you about the development of human personalities and cognitive talents?

Does it make sense to examine the value of a global analysis of gene expression throughout the entire brain and its implications for understanding brain function, development, evolution and disease from any perspective that does not include both the epigenetic effects of nutrient chemicals and the epigenetic effects of pheromones on intracellular signaling and stochastic gene expression in species from microbes to man?

 

About James V. Kohl 1307 Articles
James Vaughn Kohl was the first to accurately conceptualize human pheromones, and began presenting his findings to the scientific community in 1992. He continues to present to, and publish for, diverse scientific and lay audiences, while constantly monitoring the scientific presses for new information that is relevant to the development of his initial and ongoing conceptualization of human pheromones. Recently, Kohl integrated scientific evidence that pinpoints the evolved neurophysiological mechanism that links olfactory/pheromonal input to genes in hormone-secreting cells of tissue in a specific area of the brain that is primarily involved in the sensory integration of olfactory and visual input, and in the development of human sexual preferences. His award-winning 2007 article/book chapter on multisensory integration: The Mind’s Eyes: Human pheromones, neuroscience, and male sexual preferences followed an award winning 2001 publication: Human pheromones: integrating neuroendocrinology and ethology, which was coauthored by disinguished researchers from Vienna. Rarely do researchers win awards in multiple disciplines, but Kohl’s 2001 award was for neuroscience, and his 2007 “Reiss Theory” award was for social science. Kohl has worked as a medical laboratory scientist since 1974, and he has devoted more than twenty-five years to researching the relationship between the sense of smell and the development of human sexual preferences. Unlike many researchers who work with non-human subjects, medical laboratory scientists use the latest technology from many scientific disciplines to perform a variety of specialized diagnostic medical testing on people. James V. Kohl is certified with: * American Society for Clinical Pathology * American Medical Technologists James V. Kohl is a member of: * Society for Neuroscience * Society for Behavioral Neuroendocrinology * Association for Chemoreception Sciences * Society for the Scientific Study of Sexuality * International Society for Human Ethology * American Society for Clinical Laboratory Science * Mensa, the international high IQ society