Ecological validity and biological plausibility: Blue eyes and dark skin (2)

Rethinking Pre-Agricultural Humans

Analysis of a 7,000-year-old human genome suggests that Mesolithic people had relatively dark skin and had begun to evolve pathogen resistance characteristic of modern Europeans.

By Tracy Vence | January 28, 2014

Excerpt: “Also interesting was that the researchers found that the ancient human carried ancestral alleles in several skin pigmentation genes, leading them to conclude that he likely had dark skin and light eyes.”

My comment to “The Scientist”

See: “Table 1 | Mesolithic genome allelic state at 10 nonsynonymous variants recently selected in Europeans

Their table lists nutrient-dependent SNPs; amino acid substitutions; and function(s). In my model, these are also epigenetically-effected by the metabolism of nutrients to pheromones that control the physiology of reproduction in species from microbes to man.

Olfactory-Based Fat Discrimination in Humans” links fat detection and nutrient uptake from the bottom-up via conserved molecular mechanisms.

Our sensitivity to human body odors links them from the top-down to the pheromone-controlled physiology of reproduction via the same signaling pathway found in yeasts (see our 1996 Hormones and Behavior review).

Therefore, this representation of changes in skin pigmentation and changes in eye color appears to exemplify nutrient-dependent pheromone-controlled ecological adaptations that have been consistently attributed to mutation-initiated natural selection.

If, as suggested, de novo mutations were involved, the biological plausibility and ecological validity of the theory of mutation-driven evolution could be compared to the likelihood that the changes in skin pigmentation and eye color during a relatively short time were due to nutrient-dependent de novo gene creation sans mutations.

About James V. Kohl 1308 Articles
James Vaughn Kohl was the first to accurately conceptualize human pheromones, and began presenting his findings to the scientific community in 1992. He continues to present to, and publish for, diverse scientific and lay audiences, while constantly monitoring the scientific presses for new information that is relevant to the development of his initial and ongoing conceptualization of human pheromones. Recently, Kohl integrated scientific evidence that pinpoints the evolved neurophysiological mechanism that links olfactory/pheromonal input to genes in hormone-secreting cells of tissue in a specific area of the brain that is primarily involved in the sensory integration of olfactory and visual input, and in the development of human sexual preferences. His award-winning 2007 article/book chapter on multisensory integration: The Mind’s Eyes: Human pheromones, neuroscience, and male sexual preferences followed an award winning 2001 publication: Human pheromones: integrating neuroendocrinology and ethology, which was coauthored by disinguished researchers from Vienna. Rarely do researchers win awards in multiple disciplines, but Kohl’s 2001 award was for neuroscience, and his 2007 “Reiss Theory” award was for social science. Kohl has worked as a medical laboratory scientist since 1974, and he has devoted more than twenty-five years to researching the relationship between the sense of smell and the development of human sexual preferences. Unlike many researchers who work with non-human subjects, medical laboratory scientists use the latest technology from many scientific disciplines to perform a variety of specialized diagnostic medical testing on people. James V. Kohl is certified with: * American Society for Clinical Pathology * American Medical Technologists James V. Kohl is a member of: * Society for Neuroscience * Society for Behavioral Neuroendocrinology * Association for Chemoreception Sciences * Society for the Scientific Study of Sexuality * International Society for Human Ethology * American Society for Clinical Laboratory Science * Mensa, the international high IQ society