James A. Shapiro Author, ‘Evolution: A View from the 21st Century’; Professor of Microbiology, University of Chicago
Posted: 12/05/2013 3:57 pm
Excerpt: “Uncovering the molecular mechanisms by which living organisms modify their genomes is a major accomplishment of late 20th Century molecular biology.” Collectively, I call these processes Natural Genetic Engineering.
Symbiogenetic cell fusions, horizontal DNA transfer, mutagenic DNA repair, reverse transcription of RNA into DNA, mobile genetic elements, interspecific hybridization and whole genome doubling are only some of the topics discussed in my book.”
My comment: The topics in Shapiro’s book could be framed in the context of RNA-directed DNA methylation and RNA-mediated events that link amino acid substitutions to cell type differentiation in species from microbes to man. For example, Dobzhansky (1964) noted differences in amino acids and attributed them them to mutations in “Biology, molecular and organismic.” In 1973, “Nothing in Biology Makes Any Sense Except in the Light of Evolution” he noted differences in amino acid substitutions in chimps, humans, and gorillas.
Researchers have since reported on amino acid substitutions linked to morphogenesis and the physiology of reproduction in species from microbes to man. However, no one seems to have recognized that the amino acid substitutions are nutrient-dependent, and that the metabolism of nutrients to species-specific pheromones controls reproduction in all species.
This cause and effect relationship requires de novo creation of receptors that allow nutrients to enter cells, and de novo creation of chemical blends that control the physiology of reproduction (i.e., epigenetically-effected de novo creation x 2 under the biophysical constraints of adaptations).
Do you think that Natural Genetic Variation is nutrient-dependent and pheromone-controlled? If so, the conserved molecular mechanisms that enable this have been detailed in a series of my published works.
Do not tell this to the Creationists, however, they may quote me.