Comparative analysis of facts and theories

Comparative analysis of regulatory information and circuits across distant species

Excerpt: “…structural properties of regulatory networks are remarkably conserved and that orthologous regulatory factor families recognize similar binding motifs in vivo and show some similar co-associations.”

My comment: The co-associations of structure and function in the context of across species comparison are best explained in the context of what is currently known about how the epigenetic landscape becomes the physical landscape of DNA in the organized genomes of species from microbes to man.

If mutations and natural selection led to similarities in structure and function, the Laws of Physics, which biophysically constrain mutation-driven evolution, would need to be abandoned by evolutionary theorists.

If nutrient-dependent pheromone-controlled cell type differentiation via amino acid substitutions led to similarities in structure and function and to differences in structure and function, a single nutrient-dependent base pair change could conceivably lead from atom-level changes to ecological speciation without the pseudoscientific nonsense of population genetics.

See for instance: “We cannot conceive of a global external factor that could cause, during this time, parallel evolution of amino acid compositions of proteins in 15 diverse taxa that represent all three domains of life and span a wide range of lifestyles and environments. Thus, currently, the most plausible hypothesis is that we are observing a universal, intrinsic trend that emerged before the last universal common ancestor of all extant organisms.

Ask a social scientist whether pattern recognition of similarities makes more sense than recognition of differences in morphological and behavioral phenotypes to determine whether he or she is more like a bird-watcher or butterfly-collector than a serious scientist who has learned about biologically-based cause and effect.

About James V. Kohl 1308 Articles
James Vaughn Kohl was the first to accurately conceptualize human pheromones, and began presenting his findings to the scientific community in 1992. He continues to present to, and publish for, diverse scientific and lay audiences, while constantly monitoring the scientific presses for new information that is relevant to the development of his initial and ongoing conceptualization of human pheromones. Recently, Kohl integrated scientific evidence that pinpoints the evolved neurophysiological mechanism that links olfactory/pheromonal input to genes in hormone-secreting cells of tissue in a specific area of the brain that is primarily involved in the sensory integration of olfactory and visual input, and in the development of human sexual preferences. His award-winning 2007 article/book chapter on multisensory integration: The Mind’s Eyes: Human pheromones, neuroscience, and male sexual preferences followed an award winning 2001 publication: Human pheromones: integrating neuroendocrinology and ethology, which was coauthored by disinguished researchers from Vienna. Rarely do researchers win awards in multiple disciplines, but Kohl’s 2001 award was for neuroscience, and his 2007 “Reiss Theory” award was for social science. Kohl has worked as a medical laboratory scientist since 1974, and he has devoted more than twenty-five years to researching the relationship between the sense of smell and the development of human sexual preferences. Unlike many researchers who work with non-human subjects, medical laboratory scientists use the latest technology from many scientific disciplines to perform a variety of specialized diagnostic medical testing on people. James V. Kohl is certified with: * American Society for Clinical Pathology * American Medical Technologists James V. Kohl is a member of: * Society for Neuroscience * Society for Behavioral Neuroendocrinology * Association for Chemoreception Sciences * Society for the Scientific Study of Sexuality * International Society for Human Ethology * American Society for Clinical Laboratory Science * Mensa, the international high IQ society