A molecular visualizer of worthwhile molecular biology

Ruben Gonzalez Jr.: Molecular Visualizer

Associate Professor and Director of Graduate Studies, Department of Chemistry, Columbia University. Age 42

By Jef Akst | September 1, 2014

Excerpt: “Much of his group’s current work involves extending discoveries about translation in E. coli to the process in eukaryotes, with an eye toward human health and disease.”

My comment: That sums up the frustration that other serious scientists must share when they hear pseudoscientific nonsense touted about mutations, natural selection, and the evolution of biodiversity. The pseudoscientists often cite Lenski’s experiments as proof of evolution. See: The Man Who Bottled Evolution. For contrast, serious scientists know that all organisms compete for sources of carbon that sustain the molecular mechanisms of life cycles. The results of that competition exemplify how biophysically-constrained nutrient-dependent protein biosynthesis and degradation in species from microbes to man link ecological variation to the nutrient-dependent RNA-mediated pheromone-controlled physiology of reproduction.

It has become clear that RNA-mediated events link ecological variation to nutrient-dependent amino acid substitutions that differentiate cell types. Cell type differentiation in species is controlled by the metabolism of nutrients to species-specific pheromones. The pheromones control the species-specific physiology of reproduction, which leads to ecological adaptations (see for review Kohl, 2013). Meanwhile, those with no understanding of biologically-based cause and effect comment on mutations, natural selection, and the evolution of biodiversity as if an evolutionary event had ever been described that linked Darwin’s ‘conditions of life’ from ecological variation to ecological adaptation via mutations. (No evolutionary event = no evolution via mutations and natural selection.)

They display their ignorance, albeit anonymously, in discussion groups that might otherwise facilitate advances. Instead, the discussion groups facilitate the spread of pseudoscientific nonsense and other nonsense at a time when others make progress by ignoring evolutionary theory, which is what Dobzhansky (1964) suggested they do 50 years ago. “…the only worthwhile biology is molecular biology. All else is “bird watching” or “butterfly collecting.” Bird watching and butterfly collecting are occupations manifestly unworthy of serious scientists!”

What if serious scientist, like Ruben Gonzalez Jr., whose visions have enabled them to detail how the epigenetic landscape is linked to the physical landscape of DNA in organized genomes via RNA-mediated events, were still reporting the results of their experiments in terms of mutations and evolution of morphological phenotypes? Could any perspective on RNA and dynamic nuclear organization or Combating Evolution to Fight Disease be used to make scientific progress under conditions of extreme ignorance displayed by theorists? Did the pseudoscientists never think to ask a serious scientist about the RNA-mediated physiology of reproduction or the requirement for the concurrent ecological adaptations of morphological and behavioral phenotypes? How much longer can pseudoscientists continue to spread their ignorance before it leads to the death of us all?

About James V. Kohl 1308 Articles
James Vaughn Kohl was the first to accurately conceptualize human pheromones, and began presenting his findings to the scientific community in 1992. He continues to present to, and publish for, diverse scientific and lay audiences, while constantly monitoring the scientific presses for new information that is relevant to the development of his initial and ongoing conceptualization of human pheromones. Recently, Kohl integrated scientific evidence that pinpoints the evolved neurophysiological mechanism that links olfactory/pheromonal input to genes in hormone-secreting cells of tissue in a specific area of the brain that is primarily involved in the sensory integration of olfactory and visual input, and in the development of human sexual preferences. His award-winning 2007 article/book chapter on multisensory integration: The Mind’s Eyes: Human pheromones, neuroscience, and male sexual preferences followed an award winning 2001 publication: Human pheromones: integrating neuroendocrinology and ethology, which was coauthored by disinguished researchers from Vienna. Rarely do researchers win awards in multiple disciplines, but Kohl’s 2001 award was for neuroscience, and his 2007 “Reiss Theory” award was for social science. Kohl has worked as a medical laboratory scientist since 1974, and he has devoted more than twenty-five years to researching the relationship between the sense of smell and the development of human sexual preferences. Unlike many researchers who work with non-human subjects, medical laboratory scientists use the latest technology from many scientific disciplines to perform a variety of specialized diagnostic medical testing on people. James V. Kohl is certified with: * American Society for Clinical Pathology * American Medical Technologists James V. Kohl is a member of: * Society for Neuroscience * Society for Behavioral Neuroendocrinology * Association for Chemoreception Sciences * Society for the Scientific Study of Sexuality * International Society for Human Ethology * American Society for Clinical Laboratory Science * Mensa, the international high IQ society