Nutrient chemicals in the ecological niche calibrate individual survival, and the nutrient chemicals metabolize to pheromones in the social niche, which standardize and control reproduction in all species.
What I don’t see is anyone who is integrating the ecological, social, and neurogenic niches and considering the epigenetic effects of nutrient chemicals and pheromones in the context of endocrine disruption and transgenerational epigenetic inheritance.
I may be confused about proximate and ultimate cause, especially if the role of transgenerational epigenetic inheritance is not central to the extended evolutionary synthesis. […]
There is no direct link from visual or auditory stimuli that would explain any likelihood that spectral stimuli could classically condition the response to nutrient chemical associated with food odors.
Any study that indicates no olfactory bulb neurogenesis occurs in adult humans argues against the design in biology that ensures the plasticity of our brain-directed behavioral response to novel stimuli in our environment…
Suddenly, “epigenetic rules” offer explanatory power about half-way through the book, which allows him to link everything except olfactory/pheromonal input to group selection and an attack in the last chapters on religious beliefs.
The idea that ecological niches and social niches are the determinants of neurogenic niches, like those that develop with exposure to food odors and social odors, is one that is important to consider whether we intend to look at pharmacogenomics or to better understand the development of human behavior in the context of epigenetic effects of odors on brain development.
The direct effect of food odors and social odors on signalling pathways makes the epigenetic effects of chemical cues as important to the understanding of human behavior as they are to the understanding of behavior in every other species. This is especially true for placental mammals.
In species from microbes to man receptor-mediated changes caused by nutrient chemicals and pheromones alter intracellular signaling and stochastic gene expression.
…model organisms make clear the extension of the concept to nutrient chemical and pheromone-dependent neurogenic niches, human brain development, and individual differences in behavior.
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