Tag Archive: RNA-mediated

RNA-mediated.com (topic descriptions)

The life cycle of an mRNA in a eukaryotic cell RNA is transcribed in the nucleus processing, it is transported to the cytoplasm and translated by the ribosome. Finally the mRNA is degraded

Another companion domain has been added to the ScentofEros.com; Pheromones.com, PerfumingtheMind.com collection Intro to topics/catagories at RNA-mediated.com Information that links physics, chemistry, and molecular epigenetics from ecological variation to ecological adaptations via RNA-mediated events, such as the de novo creation…
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Implicating microRNAs in cancer

terrarium eco system

Genome-wide CRISPR Screen in a Mouse Model of Tumor Growth and Metastasis Reported as: In vivo CRISPR-Cas9 screen sheds light on cancer metastasis and tumor evolution Excerpt: “Unexpectedly, the screen also implicated several microRNAs — small RNA segments that are…
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Rejecting what is known about viral microRNAs and nutrient-dependent microRNAs

terrarium eco system

Of Cells and Limits Leonard Hayflick has been unafraid to speak his mind, whether it is to upend a well-entrenched dogma or to challenge the federal government. At 86, he’s nowhere near retirement. By Anna Azvolinsky | March 1, 2015…
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Reverse phosphorylation

Genetic code

See for review: Let there be anti-entropic light (1)   Squid are hyper-editors when it comes to RNA This is a great summary of what is currently known about anti-entropic light and nutrient-dependent RNA-mediated pheromone-controlled cell type differentiation. Excerpt: “During…
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RNA-mediated repurposing in microbes and adapations in primate brains

human-evolution

Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion Excerpt: “…the C-terminal 47 amino-acids of ARHGAP11B (after lysine-220) constitute not only a unique sequence, resulting from a frameshifting deletion (fig. S10), but also are functionally distinct from their counterpart…
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RNA-mediated “repurposing” is nutrient-dependent and pheromone-controlled

rp_poster-from-jesse.jpg

 Evolutionary resurrection of flagellar motility via rewiring of the nitrogen regulation system Excerpt: The fast-spreading strain AR2F had acquired an additional point mutation in the σ54-dependent EBP gene ntrC, which alters an amino acid (R442C) within the DNA binding domain…
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From 3-D to epigenetically-effected 4-D genome make-up

terrarium eco system

Discoveries in 3-D Genome Make-Up and Genetic Changes: Clarification of differences amidst chromosome pairs and how gene expression is effected by chromosome folding Excerpt: “…offers a useful guide for future studies of the epigenome’s function in our evolution and diseases…
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Let there be anti-entropic light (1)

terrarium eco system

Summary: Light-induced amino acid substitutions link cell type differentiation in plants to nutrient-dependent pheromone-controlled reproduction in animals via the biophysically constrained chemistry of protein folding. Protein folding is perturbed by mutations that limit the ability of organisms to adapt to…
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