Tag Archive: receptor-mediated

Single-cell level assay of protein biosynthesis and degradation

terrarium eco system

High-throughput detection of miRNAs and gene-specific mRNA at the single-cell level by flow cytometry Excerpt: “We use this technique to show modulation of a microRNA critical for T-cell function, miR-155. We adapt this assay for simultaneous detection of mRNA and…
Read more

The importance of olfactory receptors

edit1

Smell Turns Up in Unexpected Places By ALEX STONEOCT. 13, 2014 Excerpt: “I’ve been arguing for the importance of these receptors for years,” said Dr. Hatt, who calls himself an ambassador of smell, and whose favorite aromas are basil, thyme…
Read more

Genomic surveillance ends our world of RNA-mediated ecological adaptations

social interaction and brain

Why is this woman smiling? 1) Identifying Recent Adaptations in Large-Scale Genomic Data Senior author: Sabeti with co-author Rinn Excerpt: “As natural selection can only act on mutations that drive phenotypic variation…”. 2) Genomic surveillance elucidates Ebola virus origin and…
Read more

Physics, Chemistry, and Molecular biology (PCMb)

human-evolution

Physics, Chemistry, and Molecular biology (PCMb) link ecological variation to ecological adaptations via a model of gene-cell-tissue-organ-organ system complexity that I first presented in 1992. After adding gene activation by pheromones, I co-authored a book that linked the pheromone-controlled physiology…
Read more

Nutrient-dependent erythropoiesis and anemia

Genetic code

A critical role for mTORC1 in erythropoiesis and anemia Excerpt 1): “Cells must coordinate their rate of growth and proliferation with the availability of nutrients. mTOR , a serine-threonine kinase, is one the key proteins responsible for nutrient signaling in…
Read more

Evolutionary heritage or ecological adaptation? Racism versus reality

human-evolution

Jewish Heritage Written in DNA Fully sequenced genomes of more than 100 Ashkenazi people clarify the group’s history and provide a reference for researchers and physicians trying to pinpoint disease-associated genes. By Kate Yandell | September 9, 2014 Excerpt: These…
Read more

Nutrient-dependent non-random personality differences

neuronal-plasticity

Personality: The Random Factor Description: “Benjamin de Bivort, of Harvard, explores what fruit flies can tell us about personality, and also the random differences that develop between individuals and can’t be explained by genetics or environment.” My comment: The differences are…
Read more

Mutated or receptor-mediated skin color

terrarium eco system

Home Genetics January 3, 2014 Studies of a skin color gene across global populations reveal shared origins Excerpt: “All instances of a gene mutation that contributes to light skin color in Europeans came from the same chromosome of one person…
Read more

Human pheromones, nutrition, DNA, epigenetics

neuronal-plasticity

Natural selection for a well-nourished conspecific that is reproductively fit is ensured via the epigenetic effects of nutrient chemicals and pheromones.