Tag Archive: physical landscape

From 3-D to epigenetically-effected 4-D genome make-up

terrarium eco system

Discoveries in 3-D Genome Make-Up and Genetic Changes: Clarification of differences amidst chromosome pairs and how gene expression is effected by chromosome folding Excerpt: “…offers a useful guide for future studies of the epigenome’s function in our evolution and diseases…
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The anti-entropic force of “Nature”

Physics

Exploring the Epigenome A National Institutes of Health-funded consortium publishes 111 reference maps of DNA and histone marks. By Jenny Rood | February 18, 2015 Excerpt:  “All our cells have a copy of the same book, but they’re all reading…
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RNA-mediated epigenetic modification via DNA-methylation

human-evolution

I have repeatedly used the phrase “RNA-directed DNA methylation and RNA-mediated amino acid substitutions” in the context of links from the epigenetic landscape to the physical landscape of DNA in the organized genomes of species from microbes to man. See…
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All of “like kind” (Part 2)

human-evolution

See: All of “like kind” in the (bigger) family I’ve since tried, but failed, to succinctly express my thoughts about representations in the article All in the (bigger) family. I exceeded the allowable word count. Here they are, in the…
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Environment epigenetically shapes the immune system

human-evolution

Environment, more than genetics, shapes immune system 1) –with my emphasis Re: “There’s nothing here that is revolutionary or requires rethinking of our assumptions about how the immune system functions…” My comment: They removed assumptions about cell type differentiation by…
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Unified nutritional and molecular mechanisms

terrarium eco system

Endogenous Hydrogen Sulfide Production Is Essential for Dietary Restriction Benefits Article image: Excerpt: “…unifying nutritional and molecular mechanisms remain elusive.” Reported as Molecular mechanism behind health benefits of dietary restriction identified Excerpt 1) “Dietary restriction is a type of intervention…
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Chemical ecology and RNA-mediated control of DNA loops

terrarium eco system

DNA Loop-the-Loops A new full-genome map indicates how DNA is folded within the nuclei of human cells.By Kate Yandell | December 11, 2014 Excerpt: “…many loops were conserved among cell types, and even between mice and humans. But others seemed…
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Biologists puzzled by evolved RNAs and decaying DNA

terrarium eco system

Horizontal Transfer of Entire Genomes via Mitochondrial Fusion in the Angiosperm Amborella (December, 2013) Excerpt) “The ancestral angiosperm-wide genome duplication apparent in the Amborella genome not only serves as a genetic marker for the origin of extant angiosperms, but it…
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Intelligent viruses and cancers?

terrarium eco system

The Very Intelligent Ebola Virus Takes Front and Center Excerpt 1) “Ebola doesn’t enter the nucleus. It uses the cell’s machinery of ribosomes and transfer RNA to make proteins from the viral messengerRNA.” Excerpt 2) “Normally, mechanisms inside the nucleus…
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Are evolutionary theorists ‘nob ends’?

The past is not the key to the present

Interview – Prof Brian Cox and Robin Ince Robin Ince “Am I wrong to sometimes be scared of science idiots?” Brian Cox  “…my favoured response would be: ‘you bunch of utter nob ends’.  See also:  “The problem with today’s world…
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