Tag Archive: degradation

An epigenetic trap (the prequel)

terrarium eco system

See also: An epigenetic trap (the sequel) Excerpt: “Support for the link from one epigenetic trap to cell type differentiation was included in the molecular epigenetics section of our 1996 review, which detailed how RNA-mediated chromatin remodeling occurs.” My comment:…
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Converting sunlight to fuel: O2 and CO2 Reactions

Physics

Efficient solar-to-fuels production from a hybrid microbial–water-splitting catalyst system Abstract excerpt:  “…we report the development of a scalable, integrated bioelectrochemical system in which the bacterium Ralstonia eutropha is used to efficiently convert CO2, along with H2 and O2 produced from…
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A single amino acid substitution differentiates cell types of E. coli

Genetic code

Rare amino acid influences E. coli infection Excerpt: “They found that E. coli O157 is unable to attach itself to host tissue in high concentrations of D-Serine. Other strains, such as those that cause meningitis, thrive in the presence of…
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Removing natural selection; reshaping the horse; adjusting evolutionary theory

human-evolution

Prehistoric genomes reveal the genetic foundation and cost of horse domestication Reported as: Reshaping the horse through millennia Excerpt: “Domestication is generally associated with repeated demographic crashes. Yet, mutations that negatively impact genes are not eliminated by selection and can even…
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The future of physics predicts no future for evolutionary theory

Physics

The ever-smaller future of physics ‘Theory of everything’ captures Weinberg’s imagination in Lee Historical Lecture Excerpt: “…there are hints that the answers to fundamental questions will reveal themselves at around a million billionths — between 10­-17 and 10-19 — of…
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Jumping back: Science or Pseudoscience? (2)

human-evolution

See: Jumping back: Science or Pseudoscience? European Science’s Great Leap Backward inferred that evolutionary theory is evidence-based science: Excerpt: “… the U.S. can claim no superiority in our approach to evidence-based science, as demonstrated by the fact that nearly half…
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Biologists puzzled by evolved RNAs and decaying DNA

terrarium eco system

Horizontal Transfer of Entire Genomes via Mitochondrial Fusion in the Angiosperm Amborella (December, 2013) Excerpt) “The ancestral angiosperm-wide genome duplication apparent in the Amborella genome not only serves as a genetic marker for the origin of extant angiosperms, but it…
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We need pattern recognition, not a prologue

rp_poster-from-jesse.jpg

Prolegomenon “a preliminary discussion…; a prologue.” “… we need a mapping from genotype to phenotype, from phenotype to what is selected, and from what is selected to the new genotype (Lewontin, 1961). — cited in Prolegomenon to patterns in evolution…
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RNA-mediated genetic engineering (Part 3)

human-evolution

RCas9: A programmable RNA editing tool Excerpt: “The researchers envision a wide range of potential applications for RCas9. For example, an RCas9 tethered to a protein translation initiation factor and targeted to a specific mRNA could essentially act as a…
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Different physical locations and different molecular mechanisms of health and disease

thinking forbidden

Reappraisal of known malaria resistance loci in a large multicenter study Abstract excerpt: “The finding that G6PD deficiency has opposing effects on different fatal complications of P. falciparum infection indicates that the evolutionary origins of this common human genetic disorder…
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