Tag Archive: chromatin

The biologically-based origin of the mammalian placenta (2)

The past is not the key to the present

See also: The biologically-based origin of the mammalian placenta I’ll preface this follow-up on the origins of the mammalian placenta with comments that attest to foolishness of theoretical physicists who try to link Big Bang cosmology to neo-Darwinian theories about…
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De novo DNA methylation?

terrarium eco system

Epigenomics and the control of fate, form and function in social insects Excerpt: “De novo DNA methylation is critical for developmental divergence of female larvae towards the honeybee worker caste and is progressive [49,51].” de novo is a Latin expression…
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De novo gene Creation sans evolution of genes via mutations


Where do genes come from? – Carl Zimmer The pseudoscientific nonsense touted in this video has been refuted by decades of experimental evidence. The experimental evidence links RNA-directed DNA methylation from nutrient-dependent amino acid substitutions to the de novo Creation…
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Nutrient-dependent chromatin organization?

Snf2h-mediated chromatin organization and histone H1 dynamics govern cerebellar morphogenesis and neural maturation open access Conclusion: “…delineating the epigenetic regulation of neuronal development is crucial to our understanding of intellectual-disability disorders caused by mutations in epigenetic modifying enzymes. As a whole,…
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Evolution: innovations may have non-adaptive origins (sans mutations)


Q & A: Evolution Makes Do By Chris Palmer Evolutionary biologist Andreas Wagner argues that many evolutionary innovations may have non-adaptive origins. Excerpt: “If exaptations are pervasive, then natural selection—which few doubt is critical for the preservation and spreading of…
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Pheromones and cancer


Transcription Factor-MicroRNA-Target Gene Networks Associated with Ovarian Cancer Survival and Recurrence Excerpt: “MicroRNAs (miRNAs) are small, non-coding RNA molecules that bind to complementary sequences on target mRNA transcripts, and thus, regulate gene expression at the post-transcription stage. Transcription factors (TFs)…
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Epigenetic effects on chromatin and regulatation of gene expression (in Archaea?)

the bottom-up epigenetic effects of nutrient chemicals on speciation that are concurrently controlled by the top-down epigenetic effects of pheromones on reproduction challenges those who might rather attempt to-explain away the conserved molecular biology of adaptive evolution via random mutations theory

Epigenetic effects of viruses on cellular homeostasis


control of homeostasis by the epigenetic effects of proper nutrition and social stress inhibition might prevent our diet-driven and social stress-driven extinction.

Human pheromone- and nutrient-dependent brain development and behavior

terrarium eco system

…model organisms make clear the extension of the concept to nutrient chemical and pheromone-dependent neurogenic niches, human brain development, and individual differences in behavior.