Tag Archive: brain

From Hydra to humans vs a Lakatosian research program

translocated chromosome

Imre Lakatos Excerpt: “A Lakatosian research programme[8] is based on a hard core of theoretical assumptions that cannot be abandoned or altered without abandoning the programme altogether. More modest and specific theories that are formulated in order to explain evidence…
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Nothing new under the sun, except pseudoscientific nonsense

terrarium eco system

On the Importance of Being a Methodological Naturalist Posted on November 5, 2014 by David Sloan Wilson Excerpt: “…consider the flying spaghetti monster, a deity invented to poke fun at religion. It is ridiculous, but is there any way to prove…
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Making sense of quotes scattered across disciplines

social interaction and brain

Speaking of Science November 2014’s selection of notable quotes By The Scientist Staff | November 1, 2014 My comment: The quotes are scattered from across disciplines, but can be linked to what is known about conserved molecular mechanisms of biologically-based…
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Metabolism, fixation, health or neurodegerative disorder

neuronal-plasticity

“Shown is the location of the conserved regions encoding for the N-terminal chromo domain and the C-terminal MYST functional domain. An arrow denotes the position site of amino acid substitution E431Q.” Microarray Analysis Uncovers a Role for Tip60 in Nervous…
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Ecological variation and niche construction: 1, 2, 3

human-brain

Part 1 From its most basic expression in grazing and predatory nematodes with differences in morphological and behavioral phenotypes, neurogenic niche construction is nutrient-dependent and pheromone-controlled. One of these two worms has teeth. It also recognizes self vs other differences…
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Epigenetically-effected metabolic shifts and ecological adaptations

human-evolution

Epigenetics of Trained Innate Immunity: Documenting the epigenetic landscape of human innate immune cells reveals pathways essential for training macrophages. By Ruth Williams | September 25, 2014 [open access] Excerpt: “…they then analyzed genome-wide distributions of four epigenetic indicators of…
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Behavior (2): All responses are RNA-mediated not genetically-determined

IMG_2125

Diana Maria Petrosanu also asked: “who was the author of the article that had stolen your ideas?“ I cannot recall claiming that anyone had stolen our ideas or my ideas. See: Behavior: The first response is RNA-mediated not genetically-determined. In…
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Epigentically-effected sensory sensitivity and affects on behavior

neuronal-plasticity

Sensory-Related Neural Activity Regulates the Structure of Vascular Networks in the Cerebral Cortex A video abstract is available via the above link to the article abstract information. Reported as: Sensory Sensitivity Neuroscience News September 5, 2014 Excerpt: “…lowering neural activity…
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Nutrient-dependent chromatin organization?

Snf2h-mediated chromatin organization and histone H1 dynamics govern cerebellar morphogenesis and neural maturation open access Conclusion: “…delineating the epigenetic regulation of neuronal development is crucial to our understanding of intellectual-disability disorders caused by mutations in epigenetic modifying enzymes. As a whole,…
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Deficiencies prevent repair: Mutagens and Multivitamins

neuronal-plasticity

Mutagens and Multivitamins Not one to shy away from controversy, Bruce Ames has pitted himself against industry groups, environmentalists, and his peers through his work identifying DNA mutagens. And he’s not done yet. By Megan Scudellari | June 1, 2014…
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