Male pheromones and mental development

Genetic code
Share Button

Study finds males may contribute to offspring’s mental development before pregnancy


female mice exposed to male pheromones gave birth to infants with greater mental ability.

“This is the first study to show that pheromone exposure exerts an influence across generations in mammals,” said Sachiko Koyama…


Previously, scientists regarded pheromones as limited to the world of insects.

That is nonsense. A series of published works includes this one, which was co-authored by a Nobel Laureate: Feedback loops link odor and pheromone signaling with reproduction

The first review to link the RNA-mediated nutrient-dependent pheromone-controlled physiology of reproduction via metabolic networks and genetic networks to cell type differentiation in the context of transgenerational epigenetic effects was From Fertilization to Adult Sexual Behavior. The importance of RNA-mediated amino acid substitutions to pheromone-controlled biodiversity was subsequently detailed in Nutrient-dependent/pheromone-controlled adaptive evolution: a model.

The mouse to human model of biologically-based cause and effect was addressed in the context of my review, which was inspired by the ridiculous claims Richard L. Doty made in: The Great Pheromone Myth


Two additional recent reports link substitution of the amino acid alanine for the amino acid valine (Grossman et al., 2013) to nutrient-dependent pheromone-controlled adaptive evolution. The alanine substitution for valine does not appear to be under any selection pressure in mice. The cause-and-effect relationship was established in mice by comparing the effects of the alanine, which is under selection pressure in humans, via its substitution for valine in mice (Kamberov et al., 2013).

A subscription is required to read: Cross-generational impact of a male murine pheromone 2-sec-butyl-4,5-dihydrothiazole in female mice. See also: Chemical identification of MHC-influenced volatile compounds in mouse urine. I: Quantitative Proportions of Major Chemosignals

My comment: MHC-influenced chemosignals are mammalian pheromones, no matter what they have been called in past publications by this group’s senior scientist, or by human pheromone-deniers like “Dick” Doty. If the nutrient-dependent production of species-specific pheromones did not exert an influence on the mental ability of mammals, the ability to link the conserved molecular mechanisms of RNA-mediated cell type differentiation to the physiology of reproduction in all genera would be wasted on theorists who refuse to believe anything that does not require links from mutations to the evolution of biodiversity.

Share Button